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Sleep regulation and waking function: Lessons from chronic versus acute sleep deprivation studies

Aeschbach, D. (2014) Sleep regulation and waking function: Lessons from chronic versus acute sleep deprivation studies. 4th Chinese-German Meeting in Sleep Medicine and Research, 2014-07-25 - 2014-07-27, Yantai, China.

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Kurzfassung

In modern societies, many humans are exposed to a combination of acute and chronic sleep loss and circadian misalignment. Whereas it is known that these factors can impair alertness and cognitive performance, the contribution of each of them as well as their interaction when they operate together, are largely unknown. We therefore subjected young healthy individuals in the lab to a 3-week forced desynchrony protocol during which they were exposed to a long sleep-wake cycle (42.85 h) and a reduced sleep:wake ratio of 1:3.3. Over three weeks, the protocol therefore induced an increasing chronic sleep loss while allowing extended wake and sleep episodes to occur at all circadian phases. We quantified the occurrence of spontaneous attentional failures by hours awake (acute sleep loss), by study week (chronic sleep loss), and by circadian phase derived from plasma melatonin. It was found that chronic sleep loss 1) speeds up the rate at which inadvertent attentional failures accumulate during a wake episode, and 2) amplifies the circadian variation in attentional failures. Thus, acute and chronic sleep loss in combination with circadian phase should be considered as distinct factors that interact in a non-additive way to affect waking function. In another series of studies we compared short and long sleepers and identified trait-like individual differences in the tolerance of acute and chronic sleep loss.

elib-URL des Eintrags:https://elib.dlr.de/94934/
Dokumentart:Konferenzbeitrag (Vortrag)
Titel:Sleep regulation and waking function: Lessons from chronic versus acute sleep deprivation studies
Autoren:
AutorenInstitution oder E-Mail-AdresseAutoren-ORCID-iDORCID Put Code
Aeschbach, D.daniel.aeschbach (at) dlr.deNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
Datum:2014
Referierte Publikation:Nein
Open Access:Nein
Gold Open Access:Nein
In SCOPUS:Nein
In ISI Web of Science:Nein
Status:veröffentlicht
Stichwörter:Sleep regulation, acute sleep deprivation, chronic sleep deprivation
Veranstaltungstitel:4th Chinese-German Meeting in Sleep Medicine and Research
Veranstaltungsort:Yantai, China
Veranstaltungsart:internationale Konferenz
Veranstaltungsbeginn:25 Juli 2014
Veranstaltungsende:27 Juli 2014
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Luftfahrt
HGF - Programmthema:Luftverkehrsmanagement und Flugbetrieb
DLR - Schwerpunkt:Luftfahrt
DLR - Forschungsgebiet:L AO - Air Traffic Management and Operation
DLR - Teilgebiet (Projekt, Vorhaben):L - Faktor Mensch und Sicherheit in der Luftfahrt (alt)
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Flugphysiologie
Hinterlegt von: Martin, Sophie
Hinterlegt am:02 Feb 2015 16:18
Letzte Änderung:24 Apr 2024 20:00

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