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The HEPHAISTOS study: compliance and adherence with a novel orthotic device for calf muscle unloading

Weber, Tobias and Ducos, Michel and Yang, Pengfei and Jos, Dennis and Frings-Meuthen, Petra and Brüggemann, Gert-Peter and Bloch, W. and Rittweger, Jörn (2013) The HEPHAISTOS study: compliance and adherence with a novel orthotic device for calf muscle unloading. Journal of Musculoskeletal and Neuronal Interactions, 13 (4), pp. 487-495. International Society of Musculoskeletal and Neuronal Interactions. ISSN 1108-7161.

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The present manuscript seeks to discuss methodological aspects regarding the application of the novel unloading orthosis 'HEPHAISTOS' that has been specifically developed to study physiological effects of muscular unloading without altering the impact of gravitational loading. The 'HEPHAISTOS' has been applied in an ambulatory clinical interventional study. During gait, the 'HEPHAISTOS' significantly reduces activation and force production of calf muscles while it completely retains body mass-related force on the tibia. Eleven healthy male subjects participated in the study and followed their normal everyday lives while wearing the orthosis. Several measurement sessions have been performed to investigate the time course of structural and functional adaptations during intervention and recovery. Follow-up measurements were performed for one year after the intervention. In consideration of the experiences of a unique ambulant unloading study, organizational and methodological recommendations are discussed in this manuscript. Activity monitoring data obtained with portable accelerometers reveal unchanged gait activities and good subject compliance throughout the intervention. Moreover, electromyography (EMG) and motion data investigating gait properties on reambulation day are illustrated. These data show that during the initial steps following removal of 'HEPHAISTOS', gait was significantly asynchronous indicating an acutely altered motor control in the unloaded lower leg muscles.

Item URL in elib:https://elib.dlr.de/87982/
Document Type:Article
Title:The HEPHAISTOS study: compliance and adherence with a novel orthotic device for calf muscle unloading
AuthorsInstitution or Email of AuthorsAuthor's ORCID iD
Yang, PengfeiPengfei.Yang (at) dlr.deUNSPECIFIED
Frings-Meuthen, PetraMEUNSPECIFIED
Brüggemann, Gert-PeterDeutsche SporthhochschuleUNSPECIFIED
Bloch, W.German Sport UniversityUNSPECIFIED
Rittweger, Jörnjoern.rittweger (at) dlr.deUNSPECIFIED
Date:23 September 2013
Journal or Publication Title:Journal of Musculoskeletal and Neuronal Interactions
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In ISI Web of Science:Yes
Page Range:pp. 487-495
EditorsEmailEditor's ORCID iD
Publisher:International Society of Musculoskeletal and Neuronal Interactions
Keywords:Ambulant Unloading Intervention, Gravitational Loading, Muscular Unloading, Orthosis, Hephaistos
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Research under Space Conditions
DLR - Research theme (Project):R - Vorhaben Effects of Mikro-g und Hyper-g (old)
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Space Physiology
Deposited By: Becker, Christine
Deposited On:04 Feb 2014 08:56
Last Modified:10 Jan 2019 15:51

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