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Petechiae: Reproducible Pattern of Distribution and Increased Appearance After Bed Rest

Ganse, B and Limper, Ulrich and bühlmeier, Judith and Rittweger, Jörn (2013) Petechiae: Reproducible Pattern of Distribution and Increased Appearance After Bed Rest. Aviation, Space and Environmental Medicine, pp. 864-866. Aerospace Medical Association. DOI: DOI: 10.3357/ASEM.3567.2013 ISSN 0095-6562

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Abstract

Exposure to acceleration can cause petechial hemorrhages, called G measles. Petechiae usually start to develop between 5 and 9 G with a high interindividual variance. Centrifuge training delays the onset to higher G levels. One might expect onset at lower G levels after bed rest; however, there is no evidence in the literature. A case of petechiae formation after bed rest is presented here. Case report: Orthostatic tolerance was tested using a tilt table and lower body negative pressure before and after bed rest in both campaigns of a 2 3 21-d bed rest study with 6° head-down tilt. A 42-yr-old male Caucasian without any history of thrombosis, venous disease, hemorrhage, or petechiae, and with a negative thrombophilia screening, took part in the bed rest study as 1 out of 10 subjects. He was the only one to develop petechiae during the orthostatic tests after, but not before, bed rest in both campaigns. Petechiae were distributed throughout the lower legs and most pronounced at the shin in a stocking-like fashion, surprisingly reoccurring in an identical pattern of distribution. Petechiae appeared slowly over minutes during hyperemia. Discussion: This case indicates that prolonged bed rest decreases the threshold for petechiae formation. A reproducible distribution pattern suggests that factors predisposing to petechiae formation keep their local distribution over time (possibly due to local vessel structures). Mechanisms of adaptation and interindividual variance are unclear. Findings are of clinical relevance as such cases might occur after prolonged bed rest in patients without need of expensive testing.

Item URL in elib:https://elib.dlr.de/83615/
Document Type:Article
Title:Petechiae: Reproducible Pattern of Distribution and Increased Appearance After Bed Rest
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Ganse, BMEUNSPECIFIED
Limper, UlrichUlrich.Limper (at) dlr.deUNSPECIFIED
bühlmeier, JudithUniversity of BonnUNSPECIFIED
Rittweger, Jörnjoern.rittweger (at) dlr.deUNSPECIFIED
Date:August 2013
Journal or Publication Title:Aviation, Space and Environmental Medicine
Refereed publication:Yes
Open Access:Yes
Gold Open Access:No
In SCOPUS:Yes
In ISI Web of Science:No
DOI :DOI: 10.3357/ASEM.3567.2013
Page Range:pp. 864-866
Publisher:Aerospace Medical Association
ISSN:0095-6562
Status:Published
Keywords:G measles, petechial hemorrhages, acceleration, tilt table, LBNP
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):R - Vorhaben Systemphysiologie
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Space Physiology
Deposited By: Becker, Christine
Deposited On:03 Sep 2013 09:48
Last Modified:31 Jul 2019 19:41

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