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Magnetic Resonance Imaging and Computational Fluid Dynamics of High Frequency Oscillatory Ventilation (HFOV)

Scholz, Alexander and Krenkel, Lars and Terekov, Maxim and Friedrich, Janet and Rivoire, Julien and Köbrich, Rainer and Wolf, Ursula and Kalthoff, Daniel and David, Matthias and Wagner, Claus and Schreiber, Laura Maria (2011) Magnetic Resonance Imaging and Computational Fluid Dynamics of High Frequency Oscillatory Ventilation (HFOV). In: Fundamental Medical and Engineering Investigations on Protective Artificial Respiration Notes on Numerical Fluid Mechanics and Multidisciplinary Design, 116. Springer Verlag, Berlin Heidelberg. pp. 107-128. doi: 10.1007/978-3-642-20326-8_7 . ISBN 978-3-642-20325-1. ISSN 1612-2909.

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Official URL: http://link.springer.com/chapter/10.1007%2F978-3-642-20326-8_7#


In order to better understand the mechanisms of gas transport during High Frequency Oscillatory Ventilation (HFOV) Magnetic Resonance Imaging (MRI) with contrast gases and numerical flow simulations based on Computational Fluid Dynamics(CFD) methods are performed. Validation of these new techniques is conducted by comparing the results obtained with simplified models of the trachea and a first lung bifurcation as well as in a cast model of the upper central airways with results achieved from conventional fluid mechanical measurement techniques like e.g. Laser Doppler Anemometry (LDA). Further it is demonstrated that MRI of experimental HFOV is feasible and that Hyperpolarized 3^He allows for imaging the gas re-distribution inside the lung. Finally, numerical results of oscillatory flow in a 3^rd generation model of the lung as well as the impact of endotracheal tubes on the flow regime development in a trachea model are presented

Item URL in elib:https://elib.dlr.de/72289/
Document Type:Contribution to a Collection
Additional Information:Book Subtitle: A Collection of Papers from the DFG Funded Research Program PAR, Online ISBN: 978-3-642-20326-8
Title:Magnetic Resonance Imaging and Computational Fluid Dynamics of High Frequency Oscillatory Ventilation (HFOV)
AuthorsInstitution or Email of AuthorsAuthor's ORCID iD
Scholz, AlexanderUniversität MainzUNSPECIFIED
Terekov, MaximUniversität MainzUNSPECIFIED
Friedrich, JanetUniversität MainzUNSPECIFIED
Rivoire, JulienUniversität MainzUNSPECIFIED
Köbrich, RainerUniversität MainzUNSPECIFIED
Wolf, UrsulaUniversität MainzUNSPECIFIED
Kalthoff, DanielUniversität MainzUNSPECIFIED
David, MatthiasUniversität MainzUNSPECIFIED
Wagner, Clausclaus.wagner (at) dlr.deUNSPECIFIED
Schreiber, Laura MariaUniversität MainzUNSPECIFIED
Journal or Publication Title:Fundamental Medical and Engineering Investigations on Protective Artificial Respiration
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In ISI Web of Science:No
DOI :10.1007/978-3-642-20326-8_7
Page Range:pp. 107-128
EditorsEmailEditor's ORCID iD
Publisher:Springer Verlag, Berlin Heidelberg
Series Name:Notes on Numerical Fluid Mechanics and Multidisciplinary Design
Keywords:MRT, CFD Ventilation
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Transport
HGF - Program Themes:Terrestrial Vehicles (old)
DLR - Research area:Transport
DLR - Program:V BF - Bodengebundene Fahrzeuge
DLR - Research theme (Project):V - Next Generation Train (old)
Location: Göttingen
Institutes and Institutions:Institute of Aerodynamics and Flow Technology > Fluid Systems
Deposited By: Wagner, Prof. Dr.-Ing. Claus
Deposited On:14 Dec 2011 09:05
Last Modified:24 Apr 2015 13:21

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