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Paramecium - A modell system for studying cellular graviperception

Hemmersbach, R. and Bromeis, B. and Block, I. and Bräucker, R. and Krause, M. and Freiberger, N. and Stieber, C. and Wilczek, M. (2001) Paramecium - A modell system for studying cellular graviperception. Advances in Space Research, 27 (5), pp. 893-898.

Full text not available from this repository.

Abstract

Experiments under varied gravitational accelerations as well as in density-adjusted media showed that sensation of gravity in protists may clear gravi- responses (gravitaxis and gravikinesis) is an ideal model system to prove this hypothesis since the ciliary activity and thus the swimming behaviour is controlled by the membrane potential. It has also been assumed that the cytoplasmic mass causes a distinct stimulation of the bipolarly distributed mechano-sensitive K and Ca ion channels in the plasma membrane in dependence of the spatial orien- tation of the cell. In order to prove this hypo- thesis, different channel blockers are currently under investigation. Gadolinium did not inhibit gravitaxis in Paramecium, showing that it does not specifically block gravireceptors. Further studies concentrated on the question of whether second messengers are involved in the gravity signal trans- duction chain. Exposure to 5g for up to 10 min led to a significant increase in cAMP.

Item URL in elib:https://elib.dlr.de/4911/
Document Type:Article
Additional Information: LIDO-Berichtsjahr=2001,
Title:Paramecium - A modell system for studying cellular graviperception
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Hemmersbach, R.UNSPECIFIEDUNSPECIFIED
Bromeis, B.UNSPECIFIEDUNSPECIFIED
Block, I.UNSPECIFIEDUNSPECIFIED
Bräucker, R.UNSPECIFIEDUNSPECIFIED
Krause, M.UNSPECIFIEDUNSPECIFIED
Freiberger, N.UNSPECIFIEDUNSPECIFIED
Stieber, C.UNSPECIFIEDUNSPECIFIED
Wilczek, M.UNSPECIFIEDUNSPECIFIED
Date:2001
Journal or Publication Title:Advances in Space Research
Refereed publication:Yes
Open Access:No
Gold Open Access:No
In SCOPUS:No
In ISI Web of Science:Yes
Volume:27
Page Range:pp. 893-898
Status:Published
Keywords:graviperception, protists, cAMP, cGMP, gadolinium
HGF - Research field:Aeronautics, Space and Transport (old)
HGF - Program:Space (old)
HGF - Program Themes:W FR - Forschung unter Weltraumbedingungen (old)
DLR - Research area:Space
DLR - Program:W FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):UNSPECIFIED
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine
Deposited By: DLR-Beauftragter, elib
Deposited On:16 Sep 2005
Last Modified:06 Jan 2010 18:15

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