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Is the Renal Natriuretic Peptide Urodilatin Involved in the Regulation of Natriuresis

Gerzer, R. and Drummer, C. (1993) Is the Renal Natriuretic Peptide Urodilatin Involved in the Regulation of Natriuresis. Journal of Cardiovascular Pharmacology, 21 Suppl 2, pp. 86-87. Raven Press Ltd, New York, USA.

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Recent evidence has shown that the kidneys produce and secrete a member of the atrial natriuretic peptide family, named urodilatin. This 32-amino acid peptide does not circulate in blood, but is secreted into urine. Urodilatin excretion closely parallels renal sodium excretion under various conditions that influence body fluid regulation, such as circadian rhythm, salt ingestion, acute intra- venous sodium loading, water immersion, atrial distension, and cerebral hypernatremia. In contrast, the plasma concentration of the atrial member of the natriuretic peptide family often is only weakly and occasionally even negatively associated with natriuresis under these conditions. We conclude from these observations that urodilatinrather than atrial natriuretic pepteide might be the member of the natriuretic peptide family that is involved in the regulation of natriuresis in normal physiology.

Item URL in elib:https://elib.dlr.de/26872/
Document Type:Article
Additional Information: LIDO-Berichtsjahr=1993, pages=2,
Title:Is the Renal Natriuretic Peptide Urodilatin Involved in the Regulation of Natriuresis
AuthorsInstitution or Email of AuthorsAuthor's ORCID iDORCID Put Code
Journal or Publication Title:Journal of Cardiovascular Pharmacology
Refereed publication:Yes
Open Access:No
Gold Open Access:No
In ISI Web of Science:Yes
Volume:21 Suppl 2
Page Range:pp. 86-87
Publisher:Raven Press Ltd, New York, USA
Keywords:Urodilatin, sodium, fluid excretion, natriuresis, natriuretic peptide
HGF - Research field:UNSPECIFIED
HGF - Program:Space (old)
HGF - Program Themes:W EO - Erdbeobachtung
DLR - Research area:UNSPECIFIED
DLR - Program:W EO - Erdbeobachtung
DLR - Research theme (Project):UNSPECIFIED
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine
Deposited By: DLR-Beauftragter, elib
Deposited On:02 Apr 2006
Last Modified:27 Apr 2009 06:22

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