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Effects of Head-Down Tilt and Saline Loading on Body Weight, Fluid, and Electrolyte Homeostasis in Man

Heer, M. and Drummer, C. (1) and Baisch, F. and Maaß, H. and Gerzer, R. (1) and Kropp, J. (2) and Blomqvist, C. G. (3) (1992) Effects of Head-Down Tilt and Saline Loading on Body Weight, Fluid, and Electrolyte Homeostasis in Man. Acta Physiologica Scandinavica, S604, pp. 13-23. Blackwell Scientific Publications, Oxford, England.

Full text not available from this repository.

Abstract

We studied the effects of head-down tilt bedrest (HDT) on body weight, fluid and sodium homeostasis. A fluid load session with rapid intravenous infusion of 22 ml/kg body weight (BW) isotonic saline wasperformed before, during and after HDT. During the pre- and post HDT periods the test subjects were given a diet containing 2600 kcal/day.The energy intake was reduced to 2000 kcal/day during HDT. Water intake was kept constant at 40 ml/kg BW, sodium intake was 2.2 mmol/ kg BW and protein intake was 1.4 g/kg BW, while the daily fat and carbohydrate intake was reduced during the HDT period. As expected, plasma volume and BW changed rapidly in the beginning of HDT and during early recovery. A total body water loss of 0.6 l was observed within the second day after tilting. Plasma volume was reduced by 16% during HDT-bedrest. The time course of the body fluid loss paralleled a decrease in body sodium that then remained fairly constant during the HDT-bedrest period (except for the interference caused by the fluid loading on day S06). A restoration of body fluid and body sodium content occurred early in the recovery period. Fluid loading caused a negative fluid balance of 0.6-0.9 l over a 48 hr period following infusion regardless of the phase of the HDT study. These results demonstrate that under our strictly controlled conditions 1) HDT alters body fluid and sodium balances, 2) a standard fluid loading causes a net negative 3-day fluid balance during all phases of the study.

Item URL in elib:https://elib.dlr.de/26766/
Document Type:Article
Additional Information: LIDO-Berichtsjahr=1993, pages=10,
Title:Effects of Head-Down Tilt and Saline Loading on Body Weight, Fluid, and Electrolyte Homeostasis in Man
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Heer, M.UNSPECIFIEDUNSPECIFIED
Drummer, C. (1)UNSPECIFIEDUNSPECIFIED
Baisch, F.UNSPECIFIEDUNSPECIFIED
Maaß, H.UNSPECIFIEDUNSPECIFIED
Gerzer, R. (1)UNSPECIFIEDUNSPECIFIED
Kropp, J. (2)UNSPECIFIEDUNSPECIFIED
Blomqvist, C. G. (3)UNSPECIFIEDUNSPECIFIED
Date:1992
Journal or Publication Title:Acta Physiologica Scandinavica
Refereed publication:Yes
Open Access:No
Gold Open Access:No
In SCOPUS:No
In ISI Web of Science:Yes
Volume:S604
Page Range:pp. 13-23
Publisher:Blackwell Scientific Publications, Oxford, England
Series Name:144
Status:Published
Keywords:body sodium content, body water, body weight, plasma volume, saline infusion
HGF - Research field:UNSPECIFIED
HGF - Program:other
HGF - Program Themes:other
DLR - Research area:UNSPECIFIED
DLR - Program:no assignment
DLR - Research theme (Project):UNSPECIFIED
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine
Deposited By: DLR-Beauftragter, elib
Deposited On:02 Apr 2006
Last Modified:27 Apr 2009 06:20

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