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Response of Adrenergic Receptors to 10 Days Head-Down Tilt Bedrest

Maass, H. and Transmontano, J. and Baisch, F. (1992) Response of Adrenergic Receptors to 10 Days Head-Down Tilt Bedrest. Acta Physiologica Scandinavica, S604, pp. 61-68. Blackwell Scientific Publications, Oxford, England.

Full text not available from this repository.

Abstract

Adrenergic receptor responses to 10 days head-down tilt (HDT) bed-rest were measured in six healthy young males. The densities of alpha2-receptors on platelets, beta2-receptors on lymphocytes, and the responsiveness of beta2-receptors to isoproterenol stimulation were assessed, as were the urinary catecholamine excretion rates. The densities of alpha2- and beta2-receptors were low before HDT, and were high during HDT. While the density of alpha2-receptors decreased after HDT, that of beta2-receptors remained high. No changes in the responsiveness of beta2-receptors were observed. The urinary catecholamine levels were high before HDT, decreased during the bedrest period. After HDT urinary norepinephrine excretion increased sgnificantly. It is likely that the receptors were down-regulated before HDT in response to a situation that was perceived as being stressful. There were no changes in receptor characteristics specifically attributable to HDT.

Item URL in elib:https://elib.dlr.de/26761/
Document Type:Article
Additional Information: LIDO-Berichtsjahr=1993, pages=8,
Title:Response of Adrenergic Receptors to 10 Days Head-Down Tilt Bedrest
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Maass, H.UNSPECIFIEDUNSPECIFIED
Transmontano, J.UNSPECIFIEDUNSPECIFIED
Baisch, F.UNSPECIFIEDUNSPECIFIED
Date:1992
Journal or Publication Title:Acta Physiologica Scandinavica
Refereed publication:Yes
Open Access:No
Gold Open Access:No
In SCOPUS:No
In ISI Web of Science:Yes
Volume:S604
Page Range:pp. 61-68
Publisher:Blackwell Scientific Publications, Oxford, England
Series Name:144
Status:Published
Keywords:Catecholamines, down-regulation, lymphocytes, platelets, stress
HGF - Research field:UNSPECIFIED
HGF - Program:other
HGF - Program Themes:other
DLR - Research area:UNSPECIFIED
DLR - Program:no assignment
DLR - Research theme (Project):UNSPECIFIED
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine
Deposited By: DLR-Beauftragter, elib
Deposited On:02 Apr 2006
Last Modified:27 Apr 2009 06:20

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