Das unterschätzte biotechnologische Potenzial der Darmmikrobiota

Kurzfassung

The human gut microbiota harbors untapped potential for biotechno logical applications. Within the phylum of Bacteroidota, Phocaeicola vulgatus stands out as a promising candidate for sustainable produc tion of key platform chemicals like succinate. However, genetic engi neering of Phocaeicola sp. remains challenging due to its intricate molecular landscape. This study lays the groundwork for manipulating the central carbon pathways in Phocaeicola vulgatus, offering insights into overcoming genetic hurdles for increased succinate yields.