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TESTING LASER-STRUCTURED SURFACES AS ANTIMICROBIAL COUNTERMEASURE ON ISS – INSIGHTS INTO THE BIOFILMS & TOUCHING SURFACES PROJECTS

Siems, K. und Krämer, C. und Müller, D.W. und Schmidt, M. und Mücklich, F. und BIOFILMS research team and, Touching Surfaces research team und Moeller, R. (2023) TESTING LASER-STRUCTURED SURFACES AS ANTIMICROBIAL COUNTERMEASURE ON ISS – INSIGHTS INTO THE BIOFILMS & TOUCHING SURFACES PROJECTS. 2023 NASA Human Research Program Investigators’ Workshop, 7.-9. Februar 2023, Galveston Island, USA.

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Kurzfassung

Long term space missions and space habitat design require efficient strategies to sustain crew’s health as well as material integrity. While many microorganisms are essential to our health, there are also pathogenic microorganisms which cause infections and opportunistic pathogens which can cause infections given the right circumstances such as a weakened immune system. Due to the conditions in space, astronauts often have a compromised immune system. Due to limited treatment options as well as the inability to return to Earth, hence opportunistic pathogens can cause a threat to the crew’s health. Frequently touched surfaces can pose a key niche for microorganisms, but with the help of antimicrobial surfaces, the microbial burden could be reduced. With the introduction of antimicrobial surfaces for medical, pharmaceutical and industrial purposes the unique potential for reducing and preventing biofilm formation has been shown. Within the DLR-ESA BIOFILMS experiment on the International Space Station (ISS), we evaluate biofilm formation on various antimicrobial surfaces under spaceflight conditions. These surfaces are composed of different metals with and without specified surface texture modifications. All surfaces have undergone specific surface modification by Ultrashort Pulsed Direct Laser Interference Patterning (USP-DLIP). The BIOFILMS experiment studies the biofilm formation potential of different microbial species in microgravity on the ISS. In the scope of this, the interaction between the surfaces and bacteria, which is highly determined by topography and surface chemistry, will be investigated. Beside actively growing microorganisms on surfaces as done in BIOFILMS - another approach to monitor and reduce microbial contamination is tested in the spaceflight experiment Touching Surfaces, where different chemically and topographically surfaces including stainless steel as inert surface, brass and copper are tested. The different surfaces are placed in so-called Touch Arrays, which are installed on the ISS, schools in Germany as well as a university hospital in Germany. Here, the antimicrobial materials were touched in regular (controlled) fashion by the astronauts, participating scientists and volunteers (e.g., teachers and pupils) to determine material longevity and (short/long-term) antimicrobial functionality and efficiency as well as (public) acceptance/utilization. The data generated will be indispensable for the future selection of antimicrobial materials in support of human- and robotic-associated activities in space exploration.

elib-URL des Eintrags:https://elib.dlr.de/194336/
Dokumentart:Konferenzbeitrag (Poster)
Titel:TESTING LASER-STRUCTURED SURFACES AS ANTIMICROBIAL COUNTERMEASURE ON ISS – INSIGHTS INTO THE BIOFILMS & TOUCHING SURFACES PROJECTS
Autoren:
AutorenInstitution oder E-Mail-AdresseAutoren-ORCID-iDORCID Put Code
Siems, K.Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany; katharina.siems (at) dlr.dehttps://orcid.org/0000-0001-7349-0846NICHT SPEZIFIZIERT
Krämer, C.Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany and Department of Natural Sciences, University of Applied Sciences Bonn-Rhein-Sieg, Rheinbach, GermanyNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
Müller, D.W.Department of Materials Science an University of Saarland, Saarbrücken, GermanyNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
Schmidt, M.NICHT SPEZIFIZIERTNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
Mücklich, F.Department of Materials Science and Engineering, University of Saarland, Saarbrücken, GermanyNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
BIOFILMS research team and, Touching Surfaces research teamNICHT SPEZIFIZIERTNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
Moeller, R.Ralf.Moeller (at) dlr.dehttps://orcid.org/0000-0002-2371-0676NICHT SPEZIFIZIERT
Datum:Februar 2023
Referierte Publikation:Ja
Open Access:Nein
Gold Open Access:Nein
In SCOPUS:Nein
In ISI Web of Science:Nein
Status:veröffentlicht
Stichwörter:ISS, antimicrobial surfaces under spaceflight conditions, BIOFILMS, Touching Surfaces Project
Veranstaltungstitel:2023 NASA Human Research Program Investigators’ Workshop
Veranstaltungsort:Galveston Island, USA
Veranstaltungsart:Workshop
Veranstaltungsdatum:7.-9. Februar 2023
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:Forschung unter Weltraumbedingungen
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Projekt ISS LIFE 2.0
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Strahlenbiologie
Hinterlegt von: Kopp, Kerstin
Hinterlegt am:20 Mär 2023 08:52
Letzte Änderung:20 Mär 2023 08:52

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