THE CELLULAR RESPONSE OF PRIMARY ASTROCYTES TO HEAVY ION EXPOSURE

Roggan, M.D. and Kronenberg, J. and Wollert, E. and Hoffmann, S. and Nisar, H. and Konda, B. and Diegeler, S. and Liemersdorf, C. and Hemmersbach, R. and Hellweg, C.E. (2023) THE CELLULAR RESPONSE OF PRIMARY ASTROCYTES TO HEAVY ION EXPOSURE. 2023 NASA Human Research Program Investigators’ Workshop, 7.-9. Februar 2023, Galveston Island, USA.

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Abstract

Primary murine astrocytes were fully proficient for repair of DNA double strands breaks induced by low- and high-LET radiation (carbon and iron ions) and radioresistant as cell cycle arrests and massive cell death were not observed.

Item URL in elib:

https://elib.dlr.de/194133/

Document Type:

Conference or Workshop Item (Poster)

Title:

THE CELLULAR RESPONSE OF PRIMARY ASTROCYTES TO HEAVY ION EXPOSURE

Authors:

Authors	Institution or Email of Authors	Author's ORCID iD	ORCID Put Code
Roggan, M.D.	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Kronenberg, J.	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany and Microgravity User Support Center (MUSC), German Aerospace Center (DLR), Cologne, Germany	UNSPECIFIED	UNSPECIFIED
Wollert, E.	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany and Present address: Forschungszentrum Jülich, Jülich, Germany	UNSPECIFIED	UNSPECIFIED
Hoffmann, S.	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany and Gravitational Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany	UNSPECIFIED	UNSPECIFIED
Nisar, H.	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany	UNSPECIFIED	UNSPECIFIED
Konda, B.	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany	UNSPECIFIED	UNSPECIFIED
Diegeler, S.	Radiation Biology Department, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne and Department of Radiation Oncology, Harold C. Simmons Comprehensive Cancer Center, U.T. Southwestern Medical Center, Dallas, TX, USA	UNSPECIFIED	UNSPECIFIED
Liemersdorf, C.	UNSPECIFIED	https://orcid.org/0000-0001-8407-5226	UNSPECIFIED
Hemmersbach, R.	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Hellweg, C.E.	UNSPECIFIED	https://orcid.org/0000-0002-2223-3580	UNSPECIFIED

Date:

February 2023

Refereed publication:

Yes

Open Access:

Gold Open Access:

In SCOPUS:

In ISI Web of Science:

Status:

Published

Keywords:

Primary murine astrocytes, low- and high-LET radiation

Event Title:

2023 NASA Human Research Program Investigators’ Workshop

Event Location:

Galveston Island, USA

Event Type:

Workshop

Event Dates:

7.-9. Februar 2023

HGF - Research field:

Aeronautics, Space and Transport

HGF - Program:

Space

HGF - Program Themes:

Research under Space Conditions

DLR - Research area:

Raumfahrt

DLR - Program:

R FR - Research under Space Conditions

DLR - Research theme (Project):

R - NeuroSpace

Location:

Köln-Porz

Institutes and Institutions:

Institute of Aerospace Medicine > Radiation Biology
Institute of Aerospace Medicine > Gravitational Biology

Deposited By:

Kopp, Kerstin

Deposited On:

20 Mar 2023 08:50

Last Modified:

20 Mar 2023 08:50

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