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Baroreflex amplification by carotid sinus stimulation

Jordan, J. and Tank, J. (2023) Baroreflex amplification by carotid sinus stimulation. In: Primer on the Autonomic Nervous System Elsevier Inc./Academic Press. pp. 767-769. doi: 10.1016/B978-0-323-85492-4.00100-9. ISBN 978-0-323-85492-4.

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Official URL: https://doi.org/10.1016/B978-0-323-85492-4.00100-9


Cardiovascular diseases including arterial hypertension and congestive heart failure are often associated with an imbalance in cardiovascular autonomic control toward sympathetic predominance. Baroreflex activation could target the imbalance in cardiovascular autonomic control, and studies in the last years determined whether amplification of afferent carotid baroreflex signaling could be beneficial. Two different approaches have been developed to augment carotid baroreflex activation. Electrodes placed near the carotid sinus can electrically activate baroreceptors or baroreflex afferents. Another approach is placement of specialized vascular stents changing vascular geometry in the carotid sinus. Thus far, none of these treatments has been shown to reduce cardiovascular morbidity or mortality in sufficiently large controlled clinical trials.

Item URL in elib:https://elib.dlr.de/193791/
Document Type:Book Section
Title:Baroreflex amplification by carotid sinus stimulation
AuthorsInstitution or Email of AuthorsAuthor's ORCID iDORCID Put Code
Jordan, J.UNSPECIFIEDhttps://orcid.org/0000-0003-4518-0706UNSPECIFIED
Tank, J.UNSPECIFIEDhttps://orcid.org/0000-0002-5672-1187UNSPECIFIED
Date:19 January 2023
Journal or Publication Title:Primer on the Autonomic Nervous System
Refereed publication:Yes
Open Access:No
Gold Open Access:No
In ISI Web of Science:No
Page Range:pp. 767-769
EditorsEmailEditor's ORCID iDORCID Put Code
Biaggioni, I.Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University School of Medicine, NashvilleUNSPECIFIEDUNSPECIFIED
Browning, K.Department of Neural and Behavioral Sciences, Penn State College of Medicine, Hershey, PA, United StatesUNSPECIFIEDUNSPECIFIED
Fink, G.Michigan State University, College of Osteopathic Medicine, East Lansing, Michigan, United StatesUNSPECIFIEDUNSPECIFIED
Jordan, J.UNSPECIFIEDhttps://orcid.org/0000-0003-4518-0706UNSPECIFIED
Low, P.Mayo Clinic, Rochester, MN, United StatesUNSPECIFIEDUNSPECIFIED
Paton, J.F.R.Manaaki Manawa e The Centre for Heart Reseach, Department of Physiology, Faculty of Health and Medical Sciences, University of Auckland, Auckland, New ZealandUNSPECIFIEDUNSPECIFIED
Publisher:Elsevier Inc./Academic Press
Keywords:Baroreflexes; Blood pressure; Cardiovascular; Carotid sinus stimulation; Heart failure; Hypertension; Muscle sympathetic nerve activity
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Research under Space Conditions
DLR - Research theme (Project):R - CardioBrain
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine
Institute of Aerospace Medicine > Cardiovascular Medicine in Aerospace
Institute of Aerospace Medicine > Leitungsbereich ME
Deposited By: Schrage, Larissa
Deposited On:08 Feb 2023 09:21
Last Modified:19 Oct 2023 15:14

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