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Euglena, a Gravitactic Flagellate of Multiple Usages

Häder, Donald-P. und Hemmersbach, Ruth (2022) Euglena, a Gravitactic Flagellate of Multiple Usages. Life, 12 (10), Seite 1522. Multidisciplinary Digital Publishing Institute (MDPI). doi: 10.3390/life12101522. ISSN 2075-1729.

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Offizielle URL: https://www.mdpi.com/2075-1729/12/10/1522

Kurzfassung

Human exploration of space and other celestial bodies bears a multitude of challenges. The Earth-bound supply of material and food is restricted, and in situ resource utilisation (ISRU) is a prerequisite. Excellent candidates for delivering several services are unicellular algae, such as the space-approved flagellate Euglena gracilis. This review summarizes the main characteristics of this unicellular organism. Euglena has been exposed on various platforms that alter the impact of gravity to analyse its corresponding gravity-dependent physiological and molecular genetic responses. The sensory transduction chain of gravitaxis in E. gracilis has been identified. The molecular gravi- (mechano-)receptors are mechanosensory calcium channels (TRP channels). The inward gated calcium binds specifically to one of several calmodulins (CaM.2), which, in turn, activates an adenylyl cyclase. This enzyme uses ATP to produce cAMP, which induces protein kinase A, followed by the phosphorylation of a motor protein in the flagellum, initiating a course correction, and, finally, resulting in gravitaxis. During long space missions, a considerable amount of food, oxygen, and water has to be carried, and the exhaled carbon dioxide has to be removed. In this context, E. gracilis is an excellent candidate for biological life support systems, since it produces oxygen by photosynthesis, takes up carbon dioxide, and is even edible. Various species and mutants of Euglena are utilized as a producer of commercial food items, as well as a source of medicines, as it produces a number of vitamins, contains numerous trace elements, and synthesizes dietary proteins, lipids, and the reserve molecule paramylon. Euglena has anti-inflammatory, -oxidant, and -obesity properties.

elib-URL des Eintrags:https://elib.dlr.de/189003/
Dokumentart:Zeitschriftenbeitrag
Titel:Euglena, a Gravitactic Flagellate of Multiple Usages
Autoren:
AutorenInstitution oder E-Mail-AdresseAutoren-ORCID-iDORCID Put Code
Häder, Donald-P.Emeritus from Friedrich-Alexander-Universität, Institut für Botanik, Erlangen, GermanyNICHT SPEZIFIZIERTNICHT SPEZIFIZIERT
Hemmersbach, RuthGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Gravitational Biology, Cologne (Köln), Germanyhttps://orcid.org/0000-0001-5308-6715NICHT SPEZIFIZIERT
Datum:29 September 2022
Erschienen in:Life
Referierte Publikation:Ja
Open Access:Ja
Gold Open Access:Ja
In SCOPUS:Ja
In ISI Web of Science:Ja
Band:12
DOI:10.3390/life12101522
Seitenbereich:Seite 1522
Verlag:Multidisciplinary Digital Publishing Institute (MDPI)
Name der Reihe:Special Issue Gravitational Microbiology Research and Applications
ISSN:2075-1729
Status:veröffentlicht
Stichwörter:Euglena, flagellate, graviperception, gravitaxis, gravitational biology, regenerative life support system, in situ resource utilization, lunar habitat, Mars exploration
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:Forschung unter Weltraumbedingungen
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Gravisensorik
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Gravitationsbiologie
Hinterlegt von: Chiodo, Annette
Hinterlegt am:19 Okt 2022 09:44
Letzte Änderung:17 Nov 2022 11:02

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