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Development of a 3D printable clinostat for generating simulated microgravity under radiation

Nataniel, Maurice (2021) Development of a 3D printable clinostat for generating simulated microgravity under radiation. Bachelor's, FH Aachen, University of Applied Science, Aachen, Germany.

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Abstract

Future manned space missions to the Moon and Mars require the human body to be exposed to several weeks to months of microgravity and various space radiation. Further research on how these environments affect the human organism with the focus on human cells can use ground-based experimental platforms, such as clinostats which simulate microgravity over a long period of time. The aim of this bachelor thesis is the development, design and construction of a 3D printable clinostat for studies of organoids under simulated microgravity and simultaneous irradiation of heavy ions and X-rays. Thus, two aspects of the space environment can be modeled. To make this possible, a concept was developed based on requirements, and optimized and tested via prototypes printed using the FDM process. The result is a 3D printable clinostat. This demonstrates that small laboratory devices can be printed in a cost-effective manner. The advantage is the possibility to reprint the spare parts, but also to modify the CAD models according to the desired requirements.

Item URL in elib:https://elib.dlr.de/144739/
Document Type:Thesis (Bachelor's)
Additional Information:First Supervisor: Prof.Dr.-Ing. Markus Czupalla, FH Aachen, University of Applied Science; Second Supervisor: Dr. rer. nat. Jens Hauslage, German Aerospace Center (DLR), Institute of Aerospace Medicine, Gravitational Biology, Cologne; Third Supervisor: PhD Aidan Cowley, (ESA, Cologne)
Title:Development of a 3D printable clinostat for generating simulated microgravity under radiation
Authors:
AuthorsInstitution or Email of AuthorsAuthor's ORCID iDORCID Put Code
Nataniel, MauriceGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Gravitational Biology, CologneUNSPECIFIEDUNSPECIFIED
Date:30 April 2021
Refereed publication:Yes
Open Access:No
Number of Pages:104
Status:Published
Keywords:human cells, clinostat, simulated gravity, radiation, 3D-print, FDM, organoids
Institution:FH Aachen, University of Applied Science, Aachen, Germany
Department:Aerospace Engineering
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Research under Space Conditions
DLR - Research theme (Project):R - Life Sciences Experiments Moon
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Gravitational Biology
Deposited By: Chiodo, Annette
Deposited On:04 Nov 2021 09:14
Last Modified:04 Nov 2021 09:14

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