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Cardiovascular adaptation to simulated microgravity and countermeasure efficacy assessed by ballistocardiography and seismocardiography

Rabineau, J. and Hossein, A. and Landreani, F. and Haut, B. and Mulder, E. and Luchitskaya, E. and Tank, J. and Caiani, E.G. and Van De Borne, P. and Migeotte, P.-F. (2020) Cardiovascular adaptation to simulated microgravity and countermeasure efficacy assessed by ballistocardiography and seismocardiography. Scientific Reports, 10 (1), p. 17694. Nature Publishing Group. doi: 10.1038/s41598-020-74150-5. ISSN 2045-2322.

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Official URL: https://www.nature.com/articles/s41598-020-74150-5

Abstract

Head-down bed rest (HDBR) reproduces the cardiovascular effects of microgravity. We tested the hypothesis that regular high-intensity physical exercise (JUMP) could prevent this cardiovascular deconditioning, which could be detected using seismocardiography (SCG) and ballistocardiography (BCG). 23 healthy males were exposed to 60-day HDBR: 12 in a physical exercise group (JUMP), the others in a control group (CTRL). SCG and BCG were measured during supine controlled breathing protocols. From the linear and rotational SCG/BCG signals, the integral of kinetic energy (\(iK\)) was computed on each dimension over the cardiac cycle. At the end of HDBR, BCG rotational \(iK\) and SCG transversal \(iK\) decreased similarly for all participants (− 40% and − 44%, respectively, p < 0.05), and so did orthostatic tolerance (− 58%, p < 0.01). Resting heart rate decreased in JUMP (− 10%, p < 0.01), but not in CTRL. BCG linear \(iK\) decreased in CTRL (− 50%, p < 0.05), but not in JUMP. The changes in the systolic component of BCG linear iK were correlated to those in stroke volume and VO2 max (R = 0.44 and 0.47, respectively, p < 0.05). JUMP was less affected by cardiovascular deconditioning, which could be detected by BCG in agreement with standard markers of the cardiovascular condition. This shows the potential of BCG to easily monitor cardiac deconditioning.

Item URL in elib:https://elib.dlr.de/137105/
Document Type:Article
Title:Cardiovascular adaptation to simulated microgravity and countermeasure efficacy assessed by ballistocardiography and seismocardiography
Authors:
AuthorsInstitution or Email of AuthorsAuthor's ORCID iD
Rabineau, J.LPHYS, Université Libre de Bruxelles, Brussels, BelgiumUNSPECIFIED
Hossein, A.LPHYS, Université Libre de Bruxelles, Brussels, BelgiumUNSPECIFIED
Landreani, F.Politecnico di Milano, Biomed. Eng. Dpt.UNSPECIFIED
Haut, B.TIPs, Université Libre de Bruxelles, Brussels, Belgium.UNSPECIFIED
Mulder, E.german aerospace center (dlr), institute of aerospace medicine, biomedical science support center, cologne, germanyUNSPECIFIED
Luchitskaya, E.Federal State Budgetary Research Institution, State Scientific Center of the Russian Federation, Institute of Biomedical Problems, Russian Academy of Sciences,UNSPECIFIED
Tank, J.Cardiovascular Aerospace Medicine Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany; Jens.Tank (at) dlr.dehttps://orcid.org/0000-0002-5672-1187
Caiani, E.G.Politecnico di Milano, Biomed. Eng. Dpt.UNSPECIFIED
Van De Borne, P.Free University of Brussels (ULB)UNSPECIFIED
Migeotte, P.-F.pierre-francois.migeotte (at) elec.rma.ac.beUNSPECIFIED
Date:October 2020
Journal or Publication Title:Scientific Reports
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In SCOPUS:Yes
In ISI Web of Science:Yes
Volume:10
DOI :10.1038/s41598-020-74150-5
Page Range:p. 17694
Publisher:Nature Publishing Group
ISSN:2045-2322
Status:Published
Keywords:Cardiovascular adaptation, ballistocardiography, seismocardiography,
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Research under Space Conditions
DLR - Research theme (Project):R - Vorhaben Systemphysiologie (old)
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Leitungsbereich ME
Institute of Aerospace Medicine > Cardiovascular Medicine in Aerospace
Deposited By: Arndt, Carina
Deposited On:05 Nov 2020 17:19
Last Modified:05 Nov 2020 17:19

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