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Investigation of the radiation-induced DNA Damage Response in Human Lymphoma Cells

Beenen, Amke Carolina (2020) Investigation of the radiation-induced DNA Damage Response in Human Lymphoma Cells. Bachelor's, Rheinische Friedrich-Wilhelms Universität Bonn.

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Abstract

The aim of this Thesis was to help assess the impact of ionizing radiation on the immune system. This was based on the example of X-rays on the induction of DNA strand breaks and cell death in Jurkat cells. Focus was put on the dose and time dependency for the assessed parameters, evaluating radiosensitivity and DNA repair.

Item URL in elib:https://elib.dlr.de/136430/
Document Type:Thesis (Bachelor's)
Title:Investigation of the radiation-induced DNA Damage Response in Human Lymphoma Cells
Authors:
AuthorsInstitution or Email of AuthorsAuthor's ORCID iDORCID Put Code
Beenen, Amke CarolinaRadiation Biology Department, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany and Gravitational Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, GermanyUNSPECIFIEDUNSPECIFIED
Date:September 2020
Refereed publication:Yes
Open Access:No
Number of Pages:92
Status:Published
Keywords:ionizing radiation, immune system, DNA strand breaks, Jurkat cells
Institution:Rheinische Friedrich-Wilhelms Universität Bonn
Department:Faculty of Mathematics and Natural Sciences
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Research under Space Conditions
DLR - Research theme (Project):R - Vorhaben Strahlenbiologie (old)
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Radiation Biology
Institute of Aerospace Medicine > Gravitational Biology
Deposited By: Kopp, Kerstin
Deposited On:07 Oct 2020 10:10
Last Modified:07 Oct 2020 10:10

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