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Iron Ladies – How Desiccated Asexual Rotifer Adineta vaga Deal With X-Rays and Heavy Ions?

Hespeels, Boris and Penninckx, Sébastien and Cornet, Valérie and Bruneau, Lucie and Bopp, Cécile and Baumlé, Véronique and Redivo, Baptiste and Heuskin, Anne-Catherine and Moeller, Ralf and Fujimori, Akira and Lucas, Stephane and Van Doninck, Karine (2020) Iron Ladies – How Desiccated Asexual Rotifer Adineta vaga Deal With X-Rays and Heavy Ions? Frontiers in Microbiology, 11, p. 1792. Frontiers Media S.A.. doi: 10.3389/fmicb.2020.01792. ISSN 1664-302X.

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Official URL: http://dx.doi.org/10.3389/fmicb.2020.01792

Abstract

Space exposure experiments from the last 15 years have unexpectedly shown that several terrestrial organisms, including some multi-cellular species, are able to survive in open space without protection. The robustness of bdelloid rotifers suggests that these tiny creatures can possibly be added to the still restricted list of animals that can deal with the exposure to harsh condition of space. Bdelloids are one of the smallest animals on Earth. Living all over the world, mostly in semi-terrestrial environments, they appear to be extremely stress tolerant. Their desiccation tolerance at any stage of their life cycle is known to confer tolerance to a variety of stresses including high doses of radiation and freezing. In addition, they constitute a major scandal in evolutionary biology due to the putative absence of sexual reproduction for at least 60 million years. Adineta vaga, with its unique characteristics and a draft genome available, was selected by ESA (European Space Agency) as a model system to study extreme resistance of organisms exposed to space environment. In this manuscript, we documented the resistance of desiccated A. vaga individuals exposed to increasing doses of X-ray, protons and Fe ions. Consequences of exposure to different sources of radiation were investigated in regard to the cellular type including somatic (survival assay) and germinal cells (fertility assay). Then, the capacity of A. vaga individuals to repair DNA DSB induced by different source of radiation was investigated. Bdelloid rotifers represent a promising model in order to investigate damage induced by high or low LET radiation. The possibility of exposure both on hydrated or desiccated specimens may help to decipher contribution of direct and indirect radiation damage on biological processes. Results achieved through this study consolidate our knowledge about the radioresistance of A. vaga and improve our capacity to compare extreme resistance against radiation among living organisms including metazoan.

Item URL in elib:https://elib.dlr.de/135711/
Document Type:Article
Title:Iron Ladies – How Desiccated Asexual Rotifer Adineta vaga Deal With X-Rays and Heavy Ions?
Authors:
AuthorsInstitution or Email of AuthorsAuthor's ORCID iD
Hespeels, BorisResearch Unit in Environmental and Evolutionary Biology (URBE), Laboratory of Evolutionary Genetics and Ecology (LEGE), NAmur Research Institute for Life Sciences (NARILIS), Institute of Life, Earth & Environment (ILEE) University of Namur, Namur, BelgiumUNSPECIFIED
Penninckx, SébastienLaboratory of Analysis by Nuclear Reaction (LARN), NAmur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, BelgiumUNSPECIFIED
Cornet, ValérieResearch Unit in Environmental and Evolutionary Biology (URBE), Institute of Life, Earth & Environment (ILEE), University of Namur, Namur, BelgiumUNSPECIFIED
Bruneau, LucieResearch Unit in Environmental and Evolutionary Biology (URBE), Laboratory of Evolutionary Genetics and Ecology (LEGE) NAmur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, BelgiumUNSPECIFIED
Bopp, CécileLaboratory of Analysis by Nuclear Reaction (LARN), NAmur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, BelgiumUNSPECIFIED
Baumlé, VéroniqueResearch Unit in Environmental and Evolutionary Biology (URBE), Laboratory of Evolutionary Genetics and and Research Unit in Environmental and Evolutionary Biology (URBE), Institute of Life, Earth & Environment (ILEE), University of Namur, Namur, BelgiumUNSPECIFIED
Redivo, BaptisteResearch Unit in Environmental and Evolutionary Biology (URBE), Institute of Life, Earth & Environment (ILEE), University of Namur, Namur, BelgiumUNSPECIFIED
Heuskin, Anne-CatherineLaboratory of Analysis by Nuclear Reaction (LARN), NAmur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, BelgiumUNSPECIFIED
Moeller, RalfRadiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany and Department of Natural Sciences, University of Applied Sciences Bonn-Rhein-Sieg (BRSU), Rheinbach, Germany; ralf.moeller (at) dlr.dehttps://orcid.org/0000-0002-2371-0676
Fujimori, AkiraDepartment of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences (NIRS), Chiba, JapanUNSPECIFIED
Lucas, StephaneLaboratory of Analysis by Nuclear Reaction (LARN), NAmur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, BelgiumUNSPECIFIED
Van Doninck, KarineResearch Unit in Environmental and Evolutionary Biology (URBE), Laboratory of Evolutionary Genetics and and Research Unit in Environmental and Evolutionary Biology (URBE), Institute of Life, Earth & Environment (ILEE), University of Namur, Namur, BelgiumUNSPECIFIED
Date:31 July 2020
Journal or Publication Title:Frontiers in Microbiology
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In SCOPUS:Yes
In ISI Web of Science:Yes
Volume:11
DOI:10.3389/fmicb.2020.01792
Page Range:p. 1792
Publisher:Frontiers Media S.A.
ISSN:1664-302X
Status:Published
Keywords:bdelloid rotifer, LET, DNA damage, extremophile, astrobiology, panspermia
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Research under Space Conditions
DLR - Research theme (Project):R - Vorhaben Strahlenbiologie (old)
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Radiation Biology
Deposited By: Kopp, Kerstin
Deposited On:06 Aug 2020 13:15
Last Modified:29 Sep 2020 13:47

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