Baumstark-Khan, C. und Moeller, R. und Testard, I. und Saintigny, Y. und Hellweg, C.E. (2019) Genotoxic and Cytotoxic Responses of Recombinant Salmonella typhimurium TA1535 Induced by Simulated Space Radiation Qualities. AbSciCon 2019, 2019-06-24 - 2019-06-28, Bellevue, Washington.
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Kurzfassung
Introduction: For risk assessment, the mutagenic potential of the heavy ion component of the galactic cosmic radiation is of major concern for tumor induction as radiation late effects. The genetically modified TA1535 Salmonella typhimurium strain (SWITCH) reports on the presence of genotoxic conditions by dose dependent increase of bioluminescence induction and on the presence of cytotoxic conditions by dose dependent decrease in GFP fluorescence. By this, it is possible to analyze bacterial inactivation and mutation induction by ionizing radiation in parallel in the same cell within short time.
elib-URL des Eintrags: | https://elib.dlr.de/130290/ | ||||||||||||||||||||||||
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Dokumentart: | Konferenzbeitrag (Vortrag) | ||||||||||||||||||||||||
Titel: | Genotoxic and Cytotoxic Responses of Recombinant Salmonella typhimurium TA1535 Induced by Simulated Space Radiation Qualities | ||||||||||||||||||||||||
Autoren: |
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Datum: | 24 Juni 2019 | ||||||||||||||||||||||||
Referierte Publikation: | Ja | ||||||||||||||||||||||||
Open Access: | Ja | ||||||||||||||||||||||||
Gold Open Access: | Nein | ||||||||||||||||||||||||
In SCOPUS: | Nein | ||||||||||||||||||||||||
In ISI Web of Science: | Nein | ||||||||||||||||||||||||
Status: | veröffentlicht | ||||||||||||||||||||||||
Stichwörter: | space radiation, TA1535 Salmonella typhimurium, genotoxic and cytotoxic responses | ||||||||||||||||||||||||
Veranstaltungstitel: | AbSciCon 2019 | ||||||||||||||||||||||||
Veranstaltungsort: | Bellevue, Washington | ||||||||||||||||||||||||
Veranstaltungsart: | internationale Konferenz | ||||||||||||||||||||||||
Veranstaltungsbeginn: | 24 Juni 2019 | ||||||||||||||||||||||||
Veranstaltungsende: | 28 Juni 2019 | ||||||||||||||||||||||||
HGF - Forschungsbereich: | Luftfahrt, Raumfahrt und Verkehr | ||||||||||||||||||||||||
HGF - Programm: | Raumfahrt | ||||||||||||||||||||||||
HGF - Programmthema: | Forschung unter Weltraumbedingungen | ||||||||||||||||||||||||
DLR - Schwerpunkt: | Raumfahrt | ||||||||||||||||||||||||
DLR - Forschungsgebiet: | R FR - Forschung unter Weltraumbedingungen | ||||||||||||||||||||||||
DLR - Teilgebiet (Projekt, Vorhaben): | R - Vorhaben Strahlenbiologie (alt) | ||||||||||||||||||||||||
Standort: | Köln-Porz | ||||||||||||||||||||||||
Institute & Einrichtungen: | Institut für Luft- und Raumfahrtmedizin > Strahlenbiologie | ||||||||||||||||||||||||
Hinterlegt von: | Kopp, Kerstin | ||||||||||||||||||||||||
Hinterlegt am: | 21 Nov 2019 15:51 | ||||||||||||||||||||||||
Letzte Änderung: | 24 Apr 2024 20:33 |
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