Baumstark-Khan, Christa und Moeller, Ralf und Testard, Isabelle und Saintigny, Yannick und Hellweg, Christine E. (2019) Genotoxic and Cytotoxic Responses of Recombinant Salmonella typhimurium TA1535 Induced by Simulated Space Radiation Qualities. AbSciCon 2019, 2019-06-24 - 2019-06-28, Bellevue, Washington.
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Kurzfassung
Introduction: For risk assessment, mutagenic potential of heavy ions as component of galactic cosmic radiation is of major concern for tumor induction and radiation late effects. Genetically modified TA1535 Salmonella typhimurium (SWITCH) reveal genotoxicity by dose dependent increase of bioluminescence induction and cytotoxicity by dose-dependent decrease in GFP fluorescence. By this, bacterial inactivation and mutation induction by ionizing radiation are analyzed in parallel.
elib-URL des Eintrags: | https://elib.dlr.de/128248/ | ||||||||||||||||||||||||
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Dokumentart: | Konferenzbeitrag (Poster) | ||||||||||||||||||||||||
Titel: | Genotoxic and Cytotoxic Responses of Recombinant Salmonella typhimurium TA1535 Induced by Simulated Space Radiation Qualities | ||||||||||||||||||||||||
Autoren: |
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Datum: | 24 Juni 2019 | ||||||||||||||||||||||||
Referierte Publikation: | Ja | ||||||||||||||||||||||||
Open Access: | Ja | ||||||||||||||||||||||||
Gold Open Access: | Nein | ||||||||||||||||||||||||
In SCOPUS: | Nein | ||||||||||||||||||||||||
In ISI Web of Science: | Nein | ||||||||||||||||||||||||
Status: | veröffentlicht | ||||||||||||||||||||||||
Stichwörter: | galactic cosmic radiation, risk assessment, bacterial inactivation and mutation induction | ||||||||||||||||||||||||
Veranstaltungstitel: | AbSciCon 2019 | ||||||||||||||||||||||||
Veranstaltungsort: | Bellevue, Washington | ||||||||||||||||||||||||
Veranstaltungsart: | internationale Konferenz | ||||||||||||||||||||||||
Veranstaltungsbeginn: | 24 Juni 2019 | ||||||||||||||||||||||||
Veranstaltungsende: | 28 Juni 2019 | ||||||||||||||||||||||||
HGF - Forschungsbereich: | Luftfahrt, Raumfahrt und Verkehr | ||||||||||||||||||||||||
HGF - Programm: | Raumfahrt | ||||||||||||||||||||||||
HGF - Programmthema: | Forschung unter Weltraumbedingungen | ||||||||||||||||||||||||
DLR - Schwerpunkt: | Raumfahrt | ||||||||||||||||||||||||
DLR - Forschungsgebiet: | R FR - Forschung unter Weltraumbedingungen | ||||||||||||||||||||||||
DLR - Teilgebiet (Projekt, Vorhaben): | R - Vorhaben Strahlenbiologie (alt) | ||||||||||||||||||||||||
Standort: | Köln-Porz | ||||||||||||||||||||||||
Institute & Einrichtungen: | Institut für Luft- und Raumfahrtmedizin > Strahlenbiologie | ||||||||||||||||||||||||
Hinterlegt von: | Kopp, Kerstin | ||||||||||||||||||||||||
Hinterlegt am: | 03 Jul 2019 13:03 | ||||||||||||||||||||||||
Letzte Änderung: | 24 Apr 2024 20:31 |
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