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Bed Rest, Exercise Countermeasure and Reconditioning Effects on the Human Resting Muscle Tone System

Schoenrock, Birgit and Zander, Vanja and Dern, Sebastian and Limper, Ulrich and Mulder, Edwin and Veraksits, Alar and Viir, Ragnar and Kramer, Andreas and Stokes, Maria J. and Salanova, Michele and Peipsi, Aleko and Blottner, Dieter (2018) Bed Rest, Exercise Countermeasure and Reconditioning Effects on the Human Resting Muscle Tone System. Frontiers in Physiology, 9 (810), pp. 1-20. Frontiers Media S.A. DOI: https://doi.org/10.3389/fphys.2018.00810 ISSN 1664-042X

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Official URL: https://www.frontiersin.org/articles/10.3389/fphys.2018.00810/full

Abstract

The human resting muscle tone (HRMT) system provides structural and functional support to skeletal muscle and associated myofascial structures (tendons, fascia) in normal life. Little information is available on changes to the HRMT in bed rest. A set of dynamic oscillation mechanosignals ([Hz], [N/m], log decrement, [ms]) collected and computed by a hand-held digital palpation device (MyotonPRO) were used to study changes in tone and in key biomechanical and viscoelastic properties in global and postural skeletal muscle tendons and fascia from a non-exercise control (CTR) and an exercise (JUMP) group performing reactive jumps on a customized sledge system during a 60 days head-down tilt bed rest (RSL Study 2015–2016). A set of baseline and differential natural oscillation signal patterns were identified as key determinants in resting muscle and myofascial structures from back, thigh, calf, patellar and Achilles tendon, and plantar fascia. The greatest changes were found in thigh and calf muscle and tendon, with little change in the shoulder muscles. Functional tests (one leg jumps, electromyography) showed only trends in relevant leg muscle groups. Increased anti-Collagen-I immunoreactivity found in CTR soleus biopsy cryosections was absent from JUMP. Results allow for a muscle health status definition after chronic disuse in bed rest without and with countermeasure, and following reconditioning. Findings improve our understanding of structural and functional responses of the HRMT to disuse and exercise, may help to guide treatment in various clinical settings (e.g., muscle tone disorders, neuro-rehabilitation), and promote monitoring of muscle health and training status in personalized sport and space medicine.

Item URL in elib:https://elib.dlr.de/124656/
Document Type:Article
Title:Bed Rest, Exercise Countermeasure and Reconditioning Effects on the Human Resting Muscle Tone System
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Schoenrock, BirgitVegetative Anatomy, Charité Universitätsmedizin BerlinUNSPECIFIED
Zander, VanjaGerman Sport University Cologne, Institute of Cardiology and Sports Medicine, Cologne, GermanyUNSPECIFIED
Dern, SebastianNeuroscience Group, German Sports UniversityUNSPECIFIED
Limper, UlrichUlrich.Limper (at) dlr.dehttps://orcid.org/0000-0001-9927-4180
Mulder, EdwinGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Space Physiology, Cologne, GermanyUNSPECIFIED
Veraksits, AlarInstitute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, EstoniaUNSPECIFIED
Viir, RagnarRagnar Viir, Limited Partnership, Helsinki, FinlandUNSPECIFIED
Kramer, AndreasNeuromechanics Research Group, Sport Sciences, University of Konstanz, Konstanz, GermanyUNSPECIFIED
Stokes, Maria J.Faculty of Health Sciences, University of Southampton, Southampton, United KingdomUNSPECIFIED
Salanova, MicheleCharité - University Medicine BerlinUNSPECIFIED
Peipsi, AlekoMyoton AS, Tallinn, EstoniaUNSPECIFIED
Blottner, DieterCharité - University Medicine BerlinUNSPECIFIED
Date:3 July 2018
Journal or Publication Title:Frontiers in Physiology
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In SCOPUS:Yes
In ISI Web of Science:Yes
Volume:9
DOI :https://doi.org/10.3389/fphys.2018.00810
Page Range:pp. 1-20
Publisher:Frontiers Media S.A
ISSN:1664-042X
Status:Published
Keywords:skeletal muscle, tendon, fascia, biomechanical properties, disuse
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):R - Vorhaben Systemphysiologie
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Muscle and Bone Metabolism
Deposited By: Becker, Christine
Deposited On:11 Dec 2018 12:14
Last Modified:11 Dec 2018 12:14

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