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Torsion – an underestimated form shaping entity in bone adaptation?

Mittag, Uwe and Kriechbaumer, Andreas and Rittweger, Jörn (2018) Torsion – an underestimated form shaping entity in bone adaptation? Journal of Musculoskeletal and Neuronal Interactions, 18 (4), pp. 407-418. International Society of Musculoskeletal and Neuronal Interactions. ISSN 1108-7161

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Abstract

Objectives: There is ample agreement that the specific shape of a bone is related to the loads it has to carry. It is also believed that bones mechano-adapt in order to ‘find’ this shape. The open question is which signals constitute the determinants of this adapation. Recent in vivo experiments show that torsion is a significant load component in human tibia, and a computational study of the mechanostat has indicated that torsion could play a role in the shaping of tubular long bones. Methods: An earlier computational approach is further progressed to systematically study the relative importance of axial compression, lateral bending and axial torsion. Results: Results demonstrate that shapedriving potential towards tubular shapes is greatest for torsion, followed by bending and least for axial compression. Multiple linear regression analysis confirmed the dominant role of torsion, in particular for the 2nd moment of intertia. The obtained results were largely unaffected by starting conditions, e.g. either from a grid or through reshaping under disuse. Conclusions: Strong support has been found for the hypothesis torsion could be more important than suggested in previous studies as a component of the mechanical environment of bones. This will apply to the shafts of long bones, and also to the femoral neck

Item URL in elib:https://elib.dlr.de/124617/
Document Type:Article
Title:Torsion – an underestimated form shaping entity in bone adaptation?
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Mittag, UweUwe.Mittag (at) dlr.dehttps://orcid.org/0000-0002-8580-3085
Kriechbaumer, AndreasAndreas.Kriechbaumer (at) dlr.dehttps://orcid.org/0000-0001-7481-6000
Rittweger, JörnJoern.Rittweger (at) dlr.dehttps://orcid.org/0000-0002-2223-8963
Date:2018
Journal or Publication Title:Journal of Musculoskeletal and Neuronal Interactions
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In SCOPUS:Yes
In ISI Web of Science:Yes
Volume:18
Page Range:pp. 407-418
Publisher:International Society of Musculoskeletal and Neuronal Interactions
ISSN:1108-7161
Status:Published
Keywords:Bone Adaptation, Mechanostat, In Silico Study, Structural Mechanics
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):R - Vorhaben Systemphysiologie
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Muscle and Bone Metabolism
Deposited By: Becker, Christine
Deposited On:11 Dec 2018 12:02
Last Modified:11 Dec 2018 12:02

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