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Chishti, Arif Ali and Baumstark-Khan, Christa and Feles, Sebastian and Schmitz, Claudia and Azhar, Abid and Hellweg, Christine E. (2018) NF-κB ACTIVATION AFTER HEAVY ION EXPOSURE: INCREASING THE SENSITIVITY OF THE REPORTER SYSTEM. In: COSPAR 2018 Abstract-Book - Scientifc Assembly Abstracts. 42nd COSPAR Scientific Assembly, 2018-07-14 - 2018-07-22, Pasadena, CA, United States.
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Abstract
Biological effects of ionizing radiation are strongly influenced by the radiation quality. The biological effectiveness of accelerated heavy ions (which constitute the biologically most important radiation type in space) with medium to high linear energy transfer (LET), for affecting DNA damage response pathways as a gateway to cell death or survival, is of major concern for space missions.
| Item URL in elib: | https://elib.dlr.de/124378/ | ||||||||||||||||||||||||||||
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| Document Type: | Conference or Workshop Item (Speech) | ||||||||||||||||||||||||||||
| Title: | NF-κB ACTIVATION AFTER HEAVY ION EXPOSURE: INCREASING THE SENSITIVITY OF THE REPORTER SYSTEM | ||||||||||||||||||||||||||||
| Authors: |
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| Date: | July 2018 | ||||||||||||||||||||||||||||
| Journal or Publication Title: | COSPAR 2018 Abstract-Book - Scientifc Assembly Abstracts | ||||||||||||||||||||||||||||
| Refereed publication: | Yes | ||||||||||||||||||||||||||||
| Open Access: | Yes | ||||||||||||||||||||||||||||
| Gold Open Access: | No | ||||||||||||||||||||||||||||
| In SCOPUS: | No | ||||||||||||||||||||||||||||
| In ISI Web of Science: | No | ||||||||||||||||||||||||||||
| Status: | Published | ||||||||||||||||||||||||||||
| Keywords: | Nuclear Factor κB (NF-κB) , heavy ion exposure | ||||||||||||||||||||||||||||
| Event Title: | 42nd COSPAR Scientific Assembly | ||||||||||||||||||||||||||||
| Event Location: | Pasadena, CA, United States | ||||||||||||||||||||||||||||
| Event Type: | international Conference | ||||||||||||||||||||||||||||
| Event Start Date: | 14 July 2018 | ||||||||||||||||||||||||||||
| Event End Date: | 22 July 2018 | ||||||||||||||||||||||||||||
| HGF - Research field: | Aeronautics, Space and Transport | ||||||||||||||||||||||||||||
| HGF - Program: | Space | ||||||||||||||||||||||||||||
| HGF - Program Themes: | Research under Space Conditions | ||||||||||||||||||||||||||||
| DLR - Research area: | Raumfahrt | ||||||||||||||||||||||||||||
| DLR - Program: | R FR - Research under Space Conditions | ||||||||||||||||||||||||||||
| DLR - Research theme (Project): | R - Vorhaben Strahlenbiologie (old) | ||||||||||||||||||||||||||||
| Location: | Köln-Porz | ||||||||||||||||||||||||||||
| Institutes and Institutions: | Institute of Aerospace Medicine > Radiation Biology | ||||||||||||||||||||||||||||
| Deposited By: | Kopp, Kerstin | ||||||||||||||||||||||||||||
| Deposited On: | 10 Dec 2018 15:50 | ||||||||||||||||||||||||||||
| Last Modified: | 24 Apr 2024 20:28 |
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