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NF-κB ACTIVATION AFTER HEAVY ION EXPOSURE: INCREASING THE SENSITIVITY OF THE REPORTER SYSTEM

Chishti, Arif Ali and Baumstark-Khan, Christa and Feles, Sebastian and Schmitz, Claudia and Azhar, Abid and Hellweg, Christine E. (2018) NF-κB ACTIVATION AFTER HEAVY ION EXPOSURE: INCREASING THE SENSITIVITY OF THE REPORTER SYSTEM. In: COSPAR 2018 Abstract-Book - Scientifc Assembly Abstracts. 42nd COSPAR Scientific Assembly, 14 - 22 July 2018, Pasadena, CA, United States.

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Abstract

Biological effects of ionizing radiation are strongly influenced by the radiation quality. The biological effectiveness of accelerated heavy ions (which constitute the biologically most important radiation type in space) with medium to high linear energy transfer (LET), for affecting DNA damage response pathways as a gateway to cell death or survival, is of major concern for space missions.

Item URL in elib:https://elib.dlr.de/124378/
Document Type:Conference or Workshop Item (Speech)
Title:NF-κB ACTIVATION AFTER HEAVY ION EXPOSURE: INCREASING THE SENSITIVITY OF THE REPORTER SYSTEM
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Chishti, Arif AliKIBGE, University of Karachi, Karachi, Pakistan; arif.chishti (at) kibge.edu.pkhttps://orcid.org/0000-0002-2223-3580
Baumstark-Khan, ChristaRadiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany; christa.baumstark-khan (at) dlr.deUNSPECIFIED
Feles, SebastianRadiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany; sebastian.feles (at) dlr.deUNSPECIFIED
Schmitz, ClaudiaRadiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany; claudia.schmitz (at) dlr.deUNSPECIFIED
Azhar, AbidKIBGE, University of Karachi, Karachi, Pakistan; abid.azhar (at) kibge.edu.pkUNSPECIFIED
Hellweg, Christine E.Radiation Biology Department, German Aerospace Center (DLR), Institute of Aerospace Medicine, Linder Höhe, Köln, Germany; christine.hellweg (at) dlr.dehttps://orcid.org/0000-0002-2223-3580
Date:July 2018
Journal or Publication Title:COSPAR 2018 Abstract-Book - Scientifc Assembly Abstracts
Refereed publication:Yes
Open Access:Yes
Gold Open Access:No
In SCOPUS:No
In ISI Web of Science:No
Status:Published
Keywords:Nuclear Factor κB (NF-κB) , heavy ion exposure
Event Title:42nd COSPAR Scientific Assembly
Event Location:Pasadena, CA, United States
Event Type:international Conference
Event Dates:14 - 22 July 2018
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):R - Vorhaben Strahlenbiologie
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Radiation Biology
Deposited By: Kopp, Kerstin
Deposited On:10 Dec 2018 15:50
Last Modified:31 Jul 2019 20:22

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