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Adaptive Properties of the Amino Acid Alphabet and its Subsets

Bose, Rudrarup and Meringer, Markus and Ilardo, Melissa and Cleaves, H. James (2018) Adaptive Properties of the Amino Acid Alphabet and its Subsets. In: Artificial Life Conference Proceedings, pp. 459-460. The MIT Press Journals. ALIFE 2018, 23.-27. Jul. 2018, Tokyo, Japan. doi: 10.1162/isal_a_00085.

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Official URL: https://www.mitpressjournals.org/doi/abs/10.1162/isal_a_00085


The standard alphabet of the 20 genetically encoded amino acids is considered to have been selected during early evolution from a larger pool of α-amino acids based on its coverage of the chemical space. Chemical space is here defined by charge, size and hydrophobicity, leading to 6-tuples representing coverage, which is composed of range and evenness in these three physico-chemical properties. We summarize findings of previous studies on the adaptive properties of the 20 encoded amino acids and show how we extend these computational experiments to subsets of the standard alphabet.

Item URL in elib:https://elib.dlr.de/124035/
Document Type:Conference or Workshop Item (Speech, Poster)
Title:Adaptive Properties of the Amino Acid Alphabet and its Subsets
AuthorsInstitution or Email of AuthorsAuthor's ORCID iD
Bose, RudrarupNational Institute of Science Education and Research, Bhubaneshwar, IndiaUNSPECIFIED
Meringer, MarkusMarkus.Meringer (at) dlr.dehttps://orcid.org/0000-0001-8526-2429
Cleaves, H. JamesEarth-Life Science Institute, Tokyo Institute of TechnologyUNSPECIFIED
Date:18 July 2018
Journal or Publication Title:Artificial Life Conference Proceedings
Refereed publication:Yes
Open Access:Yes
Gold Open Access:No
In ISI Web of Science:No
DOI :10.1162/isal_a_00085
Page Range:pp. 459-460
Publisher:The MIT Press Journals
Keywords:amino acid, chemical space, early evolution, computational experiment
Event Title:ALIFE 2018
Event Location:Tokyo, Japan
Event Type:international Conference
Event Dates:23.-27. Jul. 2018
Organizer:International Society for Artificial Life
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Space Exploration
DLR - Research area:Raumfahrt
DLR - Program:R EW - Space Exploration
DLR - Research theme (Project):R - Explorationsstudien (old)
Location: Oberpfaffenhofen
Institutes and Institutions:Remote Sensing Technology Institute > Atmospheric Processors
Deposited By: Meringer, Dr.rer.nat. Markus
Deposited On:05 Dec 2018 12:23
Last Modified:31 Jul 2019 20:21

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