Quantitative Proteomic Analysis of Bacillus pumilus from Spores that Survived in Outer Space Conditions

Chiang, Abby J. and Babu Malli Mohan, Ganesh and Singh, Nitin K. and Horneck, Gerda and Venkateswaran, Kasthuri and Kalkum, Markus (2018) Quantitative Proteomic Analysis of Bacillus pumilus from Spores that Survived in Outer Space Conditions. 66TH ASMS CONFERENCE ON MASS SPECTROMETRY AND ALLIED TOPICS, 2018-06-03 - 2018-06-07, SAN DIEGO, CALIFORNIA.

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Abstract

The hardy spores of Bacillus species are well known for their resistance to unfavorable conditions such as UV and gamma radiation, hydrogen peroxide desiccation, chemical disinfection, or starvation. In particular, Bacillus pumilus strain SAFR-032 that was originally recovered from the Jet Propulsion Lab Spacecraft Assembly Facility has shown to exhibit unusually high resistance to UV radiation and peroxide treatment compared to other Bacillus species. To further understand the resistance of bacterial endospores to relevant outer space environments, spores of B. pumilus SAFR-032 were exposed for 1.5 years to selected parameters of space on board of the International Space Station (ISS). Here we are using a quantitative proteomics approach to gain insights into the resistance mechanism of B. pumilus.

Item URL in elib:

https://elib.dlr.de/120263/

Document Type:

Conference or Workshop Item (Poster)

Title:

Quantitative Proteomic Analysis of Bacillus pumilus from Spores that Survived in Outer Space Conditions

Authors:

Authors	Institution or Email of Authors	Author's ORCID iD	ORCID Put Code
Chiang, Abby J.	Beckman Research Institute of City of Hope, Duarte, CA	UNSPECIFIED	UNSPECIFIED
Babu Malli Mohan, Ganesh	Biotechnology and Planetary Protection Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA	UNSPECIFIED	UNSPECIFIED
Singh, Nitin K.	Biotechnology and Planetary Protection Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA	UNSPECIFIED	UNSPECIFIED
Horneck, Gerda	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Venkateswaran, Kasthuri	Biotechnology and Planetary Protection Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA	UNSPECIFIED	UNSPECIFIED
Kalkum, Markus	Beckman Research Institute of City of Hope, Duarte, CA	UNSPECIFIED	UNSPECIFIED

Date:

3 June 2018

Refereed publication:

Yes

Open Access:

Yes

Gold Open Access:

In SCOPUS:

In ISI Web of Science:

Status:

Published

Keywords:

Bacillus pumilus, spores, outer space conditions

Event Title:

66TH ASMS CONFERENCE ON MASS SPECTROMETRY AND ALLIED TOPICS

Event Location:

SAN DIEGO, CALIFORNIA

Event Type:

international Conference

Event Start Date:

3 June 2018

Event End Date:

7 June 2018

HGF - Research field:

Aeronautics, Space and Transport

HGF - Program:

Space

HGF - Program Themes:

Research under Space Conditions

DLR - Research area:

Raumfahrt

DLR - Program:

R FR - Research under Space Conditions

DLR - Research theme (Project):

R - Vorhaben Strahlenbiologie (old)

Location:

Köln-Porz

Institutes and Institutions:

Institute of Aerospace Medicine > Radiation Biology

Deposited By:

Kopp, Kerstin

Deposited On:

29 Jun 2018 10:15

Last Modified:

24 Apr 2024 20:24

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