Radiation-induced NF-κB activation and expression of its down-stream target genes as biomarker of radiation quality

Hellweg, Christine E. and Chishti, Arif Ali and Koch, Kristina and Feles, Sebastian and Konda, Bikash and Spitta, Luis F. and Henschenmacher, Bernd and Diegeler, Sebastian and Schmitz, Claudia and Baumstark-Khan, Christa (2018) Radiation-induced NF-κB activation and expression of its down-stream target genes as biomarker of radiation quality. EPR Biodose 2018 Conference, 2018-06-11 - 2018-06-15, Munich, Germany.

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Abstract

Activation of Nuclear Factor κB (NF-κB) and the resulting gene expression profile after exposure to different radiation qualities have been evaluated to a very limited extent. Therefore, the activation of NF-κB after exposure to low and high linear energy transfer (LET) radiation and the expression of its target genes was analyzed in human embryonic kidney (HEK) cells.

Item URL in elib:

https://elib.dlr.de/120262/

Document Type:

Conference or Workshop Item (Poster)

Title:

Radiation-induced NF-κB activation and expression of its down-stream target genes as biomarker of radiation quality

Authors:

Authors	Institution or Email of Authors	Author's ORCID iD	ORCID Put Code
Hellweg, Christine E.	UNSPECIFIED	https://orcid.org/0000-0002-2223-3580	UNSPECIFIED
Chishti, Arif Ali	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany. Present address: The Karachi Institute of Biotechnology and Genetic Engineering, University of Karachi, Karachi-75270, Pakistan	UNSPECIFIED	UNSPECIFIED
Koch, Kristina	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Feles, Sebastian	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Konda, Bikash	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Spitta, Luis F.	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Henschenmacher, Bernd	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Diegeler, Sebastian	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Schmitz, Claudia	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED
Baumstark-Khan, Christa	Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.	UNSPECIFIED	UNSPECIFIED

Date:

11 June 2018

Refereed publication:

Yes

Open Access:

Yes

Gold Open Access:

In SCOPUS:

In ISI Web of Science:

Status:

Published

Keywords:

Nuclear Factor κB (NF-κB), low and high linear energy transfer (LET) Radiation, human embryonic kidney (HEK) cells

Event Title:

EPR Biodose 2018 Conference

Event Location:

Munich, Germany

Event Type:

international Conference

Event Start Date:

11 June 2018

Event End Date:

15 June 2018

HGF - Research field:

Aeronautics, Space and Transport

HGF - Program:

Space

HGF - Program Themes:

Research under Space Conditions

DLR - Research area:

Raumfahrt

DLR - Program:

R FR - Research under Space Conditions

DLR - Research theme (Project):

R - Vorhaben Strahlenbiologie (old)

Location:

Köln-Porz

Institutes and Institutions:

Institute of Aerospace Medicine > Radiation Biology

Deposited By:

Kopp, Kerstin

Deposited On:

29 Jun 2018 10:15

Last Modified:

24 Apr 2024 20:24

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