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Computational Exploration of the Chemical Space of Nucleic Acid-Like Compounds

Meringer, Markus and Butch, Christopher J. and Burger, Pieter B. and Goodwin, Jay T. and Cleaves, H. James (2017) Computational Exploration of the Chemical Space of Nucleic Acid-Like Compounds. XVIIIth Intl Conf on Origin of Life 2017, 16.-21. Jul. 2017, San Diego, CA, USA.

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Official URL: https://www.hou.usra.edu/meetings/issol2017/pdf/4078.pdf

Abstract

Biological information storage for life as we know it is carried out by the nucleic acids DNA and RNA. However, these may be optimized end-states for life on Earth, or there may be other types of molecules which are similarly capable of carrying out these functions, perhaps used in alien biochemistries or in earlier biochemical states. A number of these have already been synthesized in the lab, however the set of molecules compatible with this function may be far larger. Understanding this wider "chemical space" may give insights into what makes the biological isomers unique, as well as whether there are other isomers more easily accessed by abiotic chemistry.

Item URL in elib:https://elib.dlr.de/115529/
Document Type:Conference or Workshop Item (Speech)
Title:Computational Exploration of the Chemical Space of Nucleic Acid-Like Compounds
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Meringer, MarkusMarkus.Meringer (at) dlr.dehttps://orcid.org/0000-0001-8526-2429
Butch, Christopher J.Earth-Life Science Institute, Tokyo Institute of TechnologyUNSPECIFIED
Burger, Pieter B.Emory UniversityUNSPECIFIED
Goodwin, Jay T.Emory UniversityUNSPECIFIED
Cleaves, H. JamesEarth-Life Science Institute, Tokyo Institute of TechnologyUNSPECIFIED
Date:July 2017
Refereed publication:No
Open Access:Yes
Gold Open Access:No
In SCOPUS:No
In ISI Web of Science:No
Status:Published
Keywords:biological information storage, DNA, RNA, alien biochemistries, abiotic chemistry, structure generation
Event Title:XVIIIth Intl Conf on Origin of Life 2017
Event Location:San Diego, CA, USA
Event Type:international Conference
Event Dates:16.-21. Jul. 2017
Organizer:ISSOL, LPI USRA, UC San Diego
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Space Science and Exploration
DLR - Research area:Raumfahrt
DLR - Program:R EW - Erforschung des Weltraums
DLR - Research theme (Project):R - Explorationsstudien
Location: Oberpfaffenhofen
Institutes and Institutions:Remote Sensing Technology Institute > Atmospheric Processors
Deposited By: Meringer, Dr.rer.nat. Markus
Deposited On:05 Dec 2017 10:15
Last Modified:31 Jul 2019 20:13

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