elib
DLR-Header
DLR-Logo -> http://www.dlr.de
DLR Portal Home | Imprint | Privacy Policy | Contact | Deutsch
Fontsize: [-] Text [+]

High-intensity flywheel exercise and recovery of atrophy after 90 days bed-rest

Belavy, Daniel and Ohshima, Hiroshi and Rittweger, Jörn and Felsenberg, Dieter (2017) High-intensity flywheel exercise and recovery of atrophy after 90 days bed-rest. BMJ Open Sport & Exercise Medicine, 24 (1), pp. 1-9. BMJ Publishing Group. DOI: 10.1136/bmjsem-2016-000196 ISSN 2055-7647

[img] PDF
598kB

Abstract

AIMS: To investigate differential muscle atrophy during bed-rest, the impact of a high-intensity concentric-eccentric (flywheel) resistance exercise countermeasure and muscle recovery after bed-rest. METHODS: Twenty-five healthy male subjects underwent 90 dayshead-down tilt bed-rest. Volume of individual lower-limb muscles was measured via MRI before, twice during and four times up to 1 year after bed-rest. Subjects were either inactive (n=16) or performed flywheel exercise every third day of bed-rest (n=9). Functional performance was assessed via countermovement jump. RESULTS: On 'intent-to-treat' analysis, flywheel prevented atrophy in the vasti (p<0.001) and reduced atrophy in the hip adductor/extensor adductor magnus (p=0.001) and ankle dorsiflexors/toe flexors (soleus (p<0.001), gastrocnemius medialis (p<0.001), gastrocnemius lateralis (p=0.02), and tibialis posterior with flexor digitorum longus (p=0.04)). Flywheel exercise was not effective for the hamstrings, gracilis, sartorius, peroneals and anterior tibial muscles. Muscle atrophy in vasti, soleus, gastrocnemius medialis, gastrocnemius lateralis and adductor magnus correlated with losses in countermovement jump performance. Muscle volume recovered within 90 days after bed-rest, however long-term after bed-rest, the inactive subjects only showed significantly increased muscle volume versus prebed-rest in a number of muscles including soleus (+4.3%), gastrocnemius medialis (+3.9%) and semimembranosus (+4.3%). This was not associated with greater countermovement jump performance. CONCLUSION: The exercise countermeasure was effective in preventing or reducing atrophy in the vasti, adductor magnus and ankle dorsiflexors/toe flexors but not the hamstrings, medial thigh muscles or peroneals and dorsiflexor muscles.

Item URL in elib:https://elib.dlr.de/113850/
Document Type:Article
Title:High-intensity flywheel exercise and recovery of atrophy after 90 days bed-rest
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Belavy, Danielcharité university medicine berlinUNSPECIFIED
Ohshima, HiroshijaxaUNSPECIFIED
Rittweger, JörnJoern.Rittweger (at) dlr.dehttps://orcid.org/0000-0002-2223-8963
Felsenberg, Dietercharité campus benjamin franklinUNSPECIFIED
Date:2017
Journal or Publication Title:BMJ Open Sport & Exercise Medicine
Refereed publication:Yes
Open Access:Yes
Gold Open Access:Yes
In SCOPUS:Yes
In ISI Web of Science:No
Volume:24
DOI :10.1136/bmjsem-2016-000196
Page Range:pp. 1-9
Publisher:BMJ Publishing Group
ISSN:2055-7647
Status:Published
Keywords:Exercise; Exercise rehabilitation; Muscle
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):R - Vorhaben Systemphysiologie
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Muscle and Bone Metabolism
Deposited By: Becker, Christine
Deposited On:05 Sep 2017 15:44
Last Modified:17 Nov 2018 05:02

Repository Staff Only: item control page

Browse
Search
Help & Contact
Information
electronic library is running on EPrints 3.3.12
Copyright © 2008-2017 German Aerospace Center (DLR). All rights reserved.