Häder, Donat-Peter and Braun, Markus and Grimm, Daniela and Hemmersbach, Ruth (2017) Gravireceptors in eukaryotes - a comparison of case studies on the cellular level. npj Microgravity, 3, p. 13. Nature Publishing Group. doi: 10.1038/s41526-017-0018-8. ISSN 2373-8065.
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Official URL: http://www.nature.com/articles/s41526-017-0018-8
Abstract
We have selected five evolutionary very different biological systems ranging from unicellular protists via algae and higher plants to human cells showing responses to the gravity vector of the Earth in order to compare their graviperception mechanisms. All these systems use a mass, which may either by a heavy statolith or the whole content of the cell heavier than the surrounding medium to operate on a gravireceptor either by exerting pressure or by pulling on a cytoskeletal element. In many cases the receptor seems to be a mechanosensitive ion channel activated by the gravitational force which allows a gated ion flux across the membrane when activated. This has been identified in many systems to be a calcium current, which in turn activates subsequent elements of the sensory transduction chain, such as calmodulin, which in turn results in the activation of ubiquitous enzymes, gene expression activation or silencing. Naturally, the subsequent responses to the gravity stimulus differ widely between the systems ranging from orientational movement and directed growth to physiological reactions and adaptation to the environmental conditions.
Item URL in elib: | https://elib.dlr.de/112741/ | ||||||||||||||||||||
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Document Type: | Article | ||||||||||||||||||||
Title: | Gravireceptors in eukaryotes - a comparison of case studies on the cellular level | ||||||||||||||||||||
Authors: |
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Date: | 28 April 2017 | ||||||||||||||||||||
Journal or Publication Title: | npj Microgravity | ||||||||||||||||||||
Refereed publication: | Yes | ||||||||||||||||||||
Open Access: | Yes | ||||||||||||||||||||
Gold Open Access: | Yes | ||||||||||||||||||||
In SCOPUS: | Yes | ||||||||||||||||||||
In ISI Web of Science: | Yes | ||||||||||||||||||||
Volume: | 3 | ||||||||||||||||||||
DOI: | 10.1038/s41526-017-0018-8 | ||||||||||||||||||||
Page Range: | p. 13 | ||||||||||||||||||||
Publisher: | Nature Publishing Group | ||||||||||||||||||||
ISSN: | 2373-8065 | ||||||||||||||||||||
Status: | Published | ||||||||||||||||||||
Keywords: | Gravireceptors, eukaryotes, cellular level, evolution, Euglena, Loxodes, Chara rhizoids, Arabidopsis roots, human cells | ||||||||||||||||||||
HGF - Research field: | Aeronautics, Space and Transport | ||||||||||||||||||||
HGF - Program: | Space | ||||||||||||||||||||
HGF - Program Themes: | Research under Space Conditions | ||||||||||||||||||||
DLR - Research area: | Raumfahrt | ||||||||||||||||||||
DLR - Program: | R FR - Research under Space Conditions | ||||||||||||||||||||
DLR - Research theme (Project): | R - Vorhaben Biowissenschaftliche Exp.-vorbereitung (old), R - Vorhaben Biowissenschaftliche Nutzerunterstützung (old) | ||||||||||||||||||||
Location: | Köln-Porz | ||||||||||||||||||||
Institutes and Institutions: | Institute of Aerospace Medicine > Gravitational Biology | ||||||||||||||||||||
Deposited By: | Duwe, Helmut | ||||||||||||||||||||
Deposited On: | 22 Jun 2017 09:52 | ||||||||||||||||||||
Last Modified: | 01 Feb 2025 04:16 |
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