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Finding NEMO – radiation induced bystander effects elicit (NF-κB) dependent survival

Diegeler, S. and Baumstark-Khan, C. and Hellweg, Christine E. (2017) Finding NEMO – radiation induced bystander effects elicit (NF-κB) dependent survival. 15th. International Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2017, 17.-19. Juni 2017, Ermatingen, Wolfsberg Castle, Lake Constance, Switzerland.

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Abstract

Radiation-induced bystander effects (RIBE) are an acknowledged issue of radiation therapy. Radiation of tumor tissue has been shown to affect non-irradiated neighboring cells in a paracrine and endocrine manner. Transduction of bystander signaling though remains to be investigated in detail. A part of the transduction is the receptor-initiated activation of signaling pathways by secreted factors of the irradiated cell during irradiation damage response. This work focusses on the activation of the transcription factor Nuclear Factor κB (NF-κB) in bystander cells after irradiation.

Item URL in elib:https://elib.dlr.de/112626/
Document Type:Conference or Workshop Item (Poster)
Title:Finding NEMO – radiation induced bystander effects elicit (NF-κB) dependent survival
Authors:
AuthorsInstitution or Email of AuthorsAuthors ORCID iD
Diegeler, S.german aerospace centre (dlr), institute of aerospace medicine, radiation biology department, linder höhe, d-51147 köln, germany; Sebastian.Diegeler (at) dlr.deUNSPECIFIED
Baumstark-Khan, C.german aerospace centre (dlr), institute of aerospace medicine, radiation biology department, linder höhe, d-51147 köln, germanyhttps://orcid.org/0000-0002-9329-0128
Hellweg, Christine E.german aerospace centre (dlr), institute of aerospace medicine, radiation biology department, linder höhe, d-51147 köln, germanyhttps://orcid.org/0000-0002-2223-3580
Date:2017
Refereed publication:Yes
Open Access:Yes
Gold Open Access:No
In SCOPUS:No
In ISI Web of Science:No
Status:Published
Keywords:Radiation-induced bystander effects (RIBE), Radiation therapy, Nuclear Factor κB (NF-κB)
Event Title:15th. International Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2017
Event Location:Ermatingen, Wolfsberg Castle, Lake Constance, Switzerland
Event Type:international Conference
Event Dates:17.-19. Juni 2017
HGF - Research field:Aeronautics, Space and Transport
HGF - Program:Space
HGF - Program Themes:Research under Space Conditions
DLR - Research area:Raumfahrt
DLR - Program:R FR - Forschung unter Weltraumbedingungen
DLR - Research theme (Project):R - Vorhaben Strahlenbiologie
Location: Köln-Porz
Institutes and Institutions:Institute of Aerospace Medicine > Radiation Biology
Deposited By: Kopp, Kerstin
Deposited On:29 Jun 2017 15:39
Last Modified:31 Jul 2019 20:09

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