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Short radius centrifuges - a new approach for life science experiments under hyper-g conditions for applications in space and beyond

Zander, Vanja und Anken, Ralf und Pesquet, Thomas und Brungs, Sonja und Latsch, Joachim (2013) Short radius centrifuges - a new approach for life science experiments under hyper-g conditions for applications in space and beyond. Recent Progress in Space Technology, 3 (1), Seiten 74-81. Bentham Science. DOI: 10.2174/18776116112029990014. ISBN ISSN: 2210-6871, eISSN: 1877-6116. ISSN 2210-6871.

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Offizielle URL: http://benthamscience.com/journal/index.php?journalID=rpst#top

Kurzfassung

A broad variety of countermeasures on the effects of weightlessness on human physiology have been developed and applied in the course of space exploration. Devices like treadmills, stretch ropes etc. have several disadvantages in common: they require a significant amount of crew time and they may not efficiently counteract the degradation of physiological structures and cellular functions. Some methods even include potentially painful or uncomfortable procedures for the astronauts. Thus, the application of Artificial Gravity (AG) generated by short radius centrifuges (they fit into space vessels) has been discussed and proposed by a number of scientists and space agencies as an alternative countermeasure during long-term space missions. Although there is a profound knowledge concerning, e.g., the cardiovascular system and immune responses acquired on long radius centrifuges, there is a remarkable lack of knowledge concerning the same issues on devices operating with short radius. In strict contrast to long radius centrifuges, there is a significant gravity gradient in the head-to-toe axis which comes along with the short radius and higher relative rotation velocity. Thus it is of utmost importance to continue investigating the effects of AG, especially by use of short radius centrifuges. The Short Arm Human Centrifuge (SAHC) at the German Aerospace Center (DLR) in Cologne, Germany, is the most advanced type of short radius centrifuges presently commercially available. Experience gained so far using the SAHC at DLR revealed that future projects on centrifuge devices with short radius should aim at a clear identification of the threshold level of the g-load, which is necessary to efficiently counteract the degradation of physical structures and an efficient support of cellular functions. A satisfying result would be combined countermeasure methods applied at a threshold concerning g-load and exposition time in the course of long-term sojourn in microgravity. Another future control or monitoring method to exactly dose AG training is heart rate variability, which offers an insight into neurovegetative and cardiovascular regulation. Centrifuges like the SAHC are also useful platforms to accommodate small biological experiments, e.g., experiments addressing the response of cultured cells to hypergravity. Here, we briefly review the issue of short radius centrifuges and also address our experience hitherto gained during a number of scientific projects carried out at the SAHC at DLR.

Dokumentart:Zeitschriftenbeitrag
Titel:Short radius centrifuges - a new approach for life science experiments under hyper-g conditions for applications in space and beyond
Autoren:
AutorenInstitution oder E-Mail-Adresse der Autoren
Zander, VanjaGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany
Anken, RalfGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany
Pesquet, ThomasEuropean Astronaut Center, European Space Agency, Linder Hoehe, D-51147 Cologne, Germany
Brungs, SonjaGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany
Latsch, JoachimInstitute of Cardiology and Sportmedicine, German Sport University Cologne, Am Sportpark Muengersdorf 6, D-50933
Datum:2013
Erschienen in:Recent Progress in Space Technology
Referierte Publikation:Ja
In Open Access:Nein
In SCOPUS:Nein
In ISI Web of Science:Nein
Band:3
DOI :10.2174/18776116112029990014
Seitenbereich:Seiten 74-81
Herausgeber:
HerausgeberInstitution und/oder E-Mail-Adresse der Herausgeber
Choi, Sang H.NASA Langley Research Center Hampton, VA, USA
Verlag:Bentham Science
ISSN:2210-6871
ISBN:ISSN: 2210-6871, eISSN: 1877-6116
Status:veröffentlicht
Stichwörter:Centrifuge, hyper-g, cardiovascular system, neurovestibular system, countermeasure, artificial gravity
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:Forschung unter Weltraumbedingungen
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Projekt :envihab
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Biomedizinisches Wissenschafts-Unterstützungszentrum
Hinterlegt von: Ralf Anken
Hinterlegt am:10 Feb 2014 09:16
Letzte Änderung:10 Feb 2014 09:16

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