Hauslage, Jens und Hemmersbach, Ruth und Schierwater, Bernd (2023) Microgravity Changes Membrane Properties and Triggers Bioluminescence in Pyrocystis noctiluca as an Approach for New Biosensor Concepts. In: Biosensors for the Marine Environment The Handbook of Environmental Chemistry, 122. Springer Link. Seiten 11-20. doi: 10.1007/698_2022_942. ISBN 978-3-031-32000-2.
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Offizielle URL: https://doi.org/10.1007/698_2022_942
Kurzfassung
Cell membranes with their well-defined chemo-physical properties play a crucial role in cellular functions and are indispensable for maintaining the physiological status of a cell. Recently, gravity-related changes in membrane fluidity and uptake of pharmaceutical substances have been observed in artificially produced membranes of liposomes. In order to test gravity impacts on in vivo cell membranes, we exposed an unicellular organism, the dinoflagellate Pyrocystis noctiluca, to microgravity conditions. P. noctiluca represents a quickly responding bioassay for membrane disturbances. It generates a luminescence signal in response to mechanical stimulation, which correlates to local changes in membrane fluidity. A free-fall of 4.7 s in a drop tower induced a significant luminescent signal demonstrating that even very short microgravity conditions induce alterations at the membrane level in in vivo cells of P. noctiluca.
elib-URL des Eintrags: | https://elib.dlr.de/197494/ | ||||||||||||||||
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Dokumentart: | Beitrag im Sammelband | ||||||||||||||||
Titel: | Microgravity Changes Membrane Properties and Triggers Bioluminescence in Pyrocystis noctiluca as an Approach for New Biosensor Concepts | ||||||||||||||||
Autoren: |
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Datum: | 29 Januar 2023 | ||||||||||||||||
Erschienen in: | Biosensors for the Marine Environment | ||||||||||||||||
Referierte Publikation: | Ja | ||||||||||||||||
Open Access: | Nein | ||||||||||||||||
Gold Open Access: | Nein | ||||||||||||||||
In SCOPUS: | Nein | ||||||||||||||||
In ISI Web of Science: | Nein | ||||||||||||||||
Band: | 122 | ||||||||||||||||
DOI: | 10.1007/698_2022_942 | ||||||||||||||||
Seitenbereich: | Seiten 11-20 | ||||||||||||||||
Herausgeber: |
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Verlag: | Springer Link | ||||||||||||||||
Name der Reihe: | The Handbook of Environmental Chemistry | ||||||||||||||||
ISBN: | 978-3-031-32000-2 | ||||||||||||||||
Status: | veröffentlicht | ||||||||||||||||
Stichwörter: | bioluminescence, dinoflagellates, drop tower, membrane fluidity microgravity, Pyrocystis noctiluca | ||||||||||||||||
HGF - Forschungsbereich: | Luftfahrt, Raumfahrt und Verkehr | ||||||||||||||||
HGF - Programm: | Raumfahrt | ||||||||||||||||
HGF - Programmthema: | Forschung unter Weltraumbedingungen | ||||||||||||||||
DLR - Schwerpunkt: | Raumfahrt | ||||||||||||||||
DLR - Forschungsgebiet: | R FR - Forschung unter Weltraumbedingungen | ||||||||||||||||
DLR - Teilgebiet (Projekt, Vorhaben): | R - Gravisensorik | ||||||||||||||||
Standort: | Köln-Porz | ||||||||||||||||
Institute & Einrichtungen: | Institut für Luft- und Raumfahrtmedizin > Gravitationsbiologie | ||||||||||||||||
Hinterlegt von: | Chiodo, Annette | ||||||||||||||||
Hinterlegt am: | 10 Okt 2023 13:07 | ||||||||||||||||
Letzte Änderung: | 10 Okt 2023 13:07 |
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