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Aspergillus niger Spores Are Highly Resistant to Space Radiation

Cortesão, Marta und de Haas, Aram und Unterbusch, Rebecca und Fujimori, Akira und Schütze, Tabea und Meyer, Vera und Moeller, Ralf (2020) Aspergillus niger Spores Are Highly Resistant to Space Radiation. Frontiers in Microbiology, 11, Seite 560. Frontiers Media S.A.. doi: 10.3389/fmicb.2020.00560. ISSN 1664-302X.

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Offizielle URL: http://dx.doi.org/10.3389/fmicb.2020.00560

Kurzfassung

The filamentous fungus Aspergillus niger is one of the main contaminants of the International Space Station (ISS). It forms highly pigmented, airborne spores that have thick cell walls and low metabolic activity, enabling them to withstand harsh conditions and colonize spacecraft surfaces. Whether A. niger spores are resistant to space radiation, and to what extent, is not yet known. In this study, spore suspensions of a wild-type and three mutant strains (with defects in pigmentation, DNA repair, and polar growth control) were exposed to X-rays, cosmic radiation (helium- and iron-ions) and UV-C (254 nm). To assess the level of resistance and survival limits of fungal spores in a long-term interplanetary mission scenario, we tested radiation doses up to 1000 Gy and 4000 J/m². For comparison, a 360-day round-trip to Mars yields a dose of 0.66 ± 0.12 Gy. Overall, wild-type spores of A. niger were able to withstand high doses of X-ray (LD₉₀ = 360 Gy) and cosmic radiation (helium-ion LD₉₀ = 500 Gy; and iron-ion LD₉₀ = 100 Gy). Drying the spores before irradiation made them more susceptible toward X-ray radiation. Notably, A. niger spores are highly resistant to UV-C radiation (LD₉₀ = 1038 J/m²), which is significantly higher than that of other radiation-resistant microorganisms (e.g., Deinococcus radiodurans). In all strains, UV-C treated spores (1000 J/m²) were shown to have decreased biofilm formation (81% reduction in wild-type spores). This study suggests that A. niger spores might not be easily inactivated by exposure to space radiation alone and that current planetary protection guidelines should be revisited, considering the high resistance of fungal spores.

elib-URL des Eintrags:https://elib.dlr.de/134619/
Dokumentart:Zeitschriftenbeitrag
Titel:Aspergillus niger Spores Are Highly Resistant to Space Radiation
Autoren:
AutorenInstitution oder E-Mail-AdresseAutoren-ORCID-iD
Cortesão, Marta*Space Microbiology Research Group, Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR e.V.), Cologne, Germany; Marta.Cortesao (at) dlr.dehttps://orcid.org/0000-0001-6603-1211
de Haas, AramSpace Microbiology Research Group, Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR e.V.), Cologne, Germany
Unterbusch, RebeccaSpace Microbiology Research Group, Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR e.V.), Cologne, Germany
Fujimori, AkiraDepartment of Basic Medical Sciences for Radiation Damages, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan
Schütze, TabeaChair of Applied and Molecular Microbiology, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany
Meyer, VeraChair of Applied and Molecular Microbiology, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany
Moeller, RalfSpace Microbiology Research Group, Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR e.V.), Cologne, Germany; ralf.moeller (at) dlr.dehttps://orcid.org/0000-0002-2371-0676
*DLR corresponding author
Datum:3 April 2020
Erschienen in:Frontiers in Microbiology
Referierte Publikation:Ja
Open Access:Ja
Gold Open Access:Ja
In SCOPUS:Ja
In ISI Web of Science:Ja
Band:11
DOI:10.3389/fmicb.2020.00560
Seitenbereich:Seite 560
Verlag:Frontiers Media S.A.
ISSN:1664-302X
Status:veröffentlicht
Stichwörter:Aspergillus niger, A. niger spores, spore survival, space, radiation, X-ray, UV, international space station
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:Forschung unter Weltraumbedingungen
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Vorhaben Strahlenbiologie (alt)
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Strahlenbiologie
Hinterlegt von: Kopp, Kerstin
Hinterlegt am:07 Apr 2020 13:10
Letzte Änderung:24 Okt 2023 15:05

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