elib
DLR-Header
DLR-Logo -> http://www.dlr.de
DLR Portal Home | Impressum | Kontakt | English
Schriftgröße: [-] Text [+]

A combination of whey protein and potassium bicarbonate supplements during head-down-tilt bed rest: Presentation of a multidisciplinary randomized controlled trial (MEP study)

Bühlmeier, Judith und Mulder, Edwin und Noppe, Alexandra und Frings-Meuthen, Petra und Angerer, Oliver und Rudwill, Floriane und Biolo, Gianni und Smith, Scott M. und Blanc, Stéphane und Heer, Martina (2014) A combination of whey protein and potassium bicarbonate supplements during head-down-tilt bed rest: Presentation of a multidisciplinary randomized controlled trial (MEP study). Acta Astronautica. ISSN 0094-5765.

Dieses Archiv kann nicht den gesamten Text zur Verfügung stellen.

Kurzfassung

Inactivity, as it appears during space flight and in bed rest, induces reduction of lean body and bone mass, glucose intolerance, and weakening of the cardiovascular system. Increased protein intake, whey protein in particular, has been proposed to counteract some of these effects, but has also been associated with negative effects on bone, likely caused by a correspondingly high ratio of acid to alkali precursors in the diet. The main hypothesis of the presented cross-over study (MEP study) was that supplementing high protein intake (1.2 g/kg body weight/d plus 0.6 g/kg body weight/d whey protein) with alkaline salts (90 mmol potassium bicarbonate/d) will maintain lean body mass during bed rest without increasing bone resorption. A 21-day head-down-tilt bed rest study was performed to examine several physiological systems in a multidisciplinary approach. Ten healthy men (age: 31±6 years; body weight: 76.5±5.6 kg) were randomly assigned to the dietary countermeasure or isocaloric control first, one test subject randomized to the dietary countermeasure first dropped out after the first campaign.

Dokumentart:Zeitschriftenbeitrag
Titel:A combination of whey protein and potassium bicarbonate supplements during head-down-tilt bed rest: Presentation of a multidisciplinary randomized controlled trial (MEP study)
Autoren:
AutorenInstitution oder E-Mail-Adresse der Autoren
Bühlmeier, JudithUniversity of Bonn, Germany
Mulder, EdwinGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Space Physiology, Cologne, Germany
Noppe, AlexandraGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany
Frings-Meuthen, PetraGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Space Physiology, Cologne, Germany
Angerer, OliverHE Space for ESA, Nordwijk The Netherlands
Rudwill, FlorianeUniversité de Strasbourg, France
Biolo, GianniUniversity of Trieste, Italy
Smith, Scott M.NASA, Johnson Space Center, Houston, USA
Blanc, StéphaneUniversité de Strasbourg, CNRS, Institut Pluridisciplinaire Hubert Curien, France
Heer, MartinaProfil Neuss GmbH, Neuss, Germany
Datum:2014
Erschienen in:Acta Astronautica
Referierte Publikation:Ja
In Open Access:Nein
In SCOPUS:Ja
In ISI Web of Science:Ja
ISSN:0094-5765
Status:akzeptierter Beitrag
Stichwörter:Immobilization, Space flight analog, Nutrition, Countermeasure, Standardization, Physical activity
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:keine Zuordnung
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R - keine Zuordnung
DLR - Teilgebiet (Projekt, Vorhaben):R -- keine Zuordnung
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin
Hinterlegt von: Alexandra Noppe
Hinterlegt am:10 Feb 2014 09:15
Letzte Änderung:10 Feb 2014 09:15

Nur für Mitarbeiter des Archivs: Kontrollseite des Eintrags

Blättern
Suchen
Hilfe & Kontakt
Informationen
electronic library verwendet EPrints 3.3.12
Copyright © 2008-2013 Deutsches Zentrum für Luft- und Raumfahrt (DLR). Alle Rechte vorbehalten.