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Simulation of microgravity for studies in gravitational biology: principles, devices and applications

Anken, Ralf (2013) Simulation of microgravity for studies in gravitational biology: principles, devices and applications. Current Biotechnology, 2 (3), Seiten 192-200. Bentham Science Publishers. DOI: 10.2174/22115501113029990012 ISBN ISSN: 2211-5501, eISSN: 2211-551X ISSN 2211-5501

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Offizielle URL: http://benthamscience.com/journal/index.php?journalID=cbiot


Scientists and technicians have been innovative to develop experimental platforms in order to achieve functional weightless conditions in their Earth-bound laboratories. As a result, various experimental platforms are available in order to perform studies with molecules or single cells up to humans and to study gravity-related mechanisms. These ground-based simulators of microgravity are not only tools to prepare spaceflight experiments, but they have been established as stand-alone facilities for gravitational research. This review provides an overview of some of the most frequently used microgravity simulators, most of which are in use at DLR´s Institute of Aerospace Medicine at Cologne, Germany. Their individual capacities but also experimental limitations, especially regarding their range of applicability for biological specimens, are exemplarily reviewed here. Overall, it is necessary to compare data achieved by using simulators with the data obtained in real microgravity. Furthermore, it should be carefully considered which kind of simulation might be the optimum for a given model organism or cell.

Titel:Simulation of microgravity for studies in gravitational biology: principles, devices and applications
AutorenInstitution oder E-Mail-AdresseAutoren-ORCID-iD
Anken, RalfGerman Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, GermanyNICHT SPEZIFIZIERT
Erschienen in:Current Biotechnology
Referierte Publikation:Ja
In Open Access:Nein
In ISI Web of Science:Nein
DOI :10.2174/22115501113029990012
Seitenbereich:Seiten 192-200
HerausgeberInstitution und/oder E-Mail-Adresse der Herausgeber
Dalby, PaulDept of Biochemical Engineering, University College London Torrington Place, WC1E 7JE, UK
Verlag:Bentham Science Publishers
ISBN:ISSN: 2211-5501, eISSN: 2211-551X
Stichwörter:Space Biology, Gravitational Biology, Gravity, Microgravity, Clinostat, Random Positioning Machine
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:Forschung unter Weltraumbedingungen
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Vorhaben Biowissenschaftliche Nutzerunterstützung
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Biomedizinisches Wissenschafts-Unterstützungszentrum
Hinterlegt von: Anken, Ralf
Hinterlegt am:10 Feb 2014 09:16
Letzte Änderung:08 Mär 2018 18:35

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