elib
DLR-Header
DLR-Logo -> http://www.dlr.de
DLR Portal Home | Impressum | Kontakt | English
Schriftgröße: [-] Text [+]

Out-of-field dose measurements in a water phantom using different radiotherapy modalities

Kaderka, R. und Schardt, D. und Durante, M. und Berger, T. und Ramm, U. und Licher, J. und La Tessa, C. (2012) Out-of-field dose measurements in a water phantom using different radiotherapy modalities. Phys. Med. Biol., 57 (16), Seiten 5059-5074. IOP PUBLISHING. DOI: 10.1088/0031-9155/57/16/5059.

Dieses Archiv kann nicht den gesamten Text zur Verfügung stellen.

Kurzfassung

This investigation focused on the characterization of the lateral dose fall-off following the irradiation of the target with photons, protons and carbon ions. A water phantom was irradiated with a rectangular field using photons, passively delivered protons as well as scanned protons and carbon ions. The lateral dose profile in the depth of the maximum dose was measured using an ion chamber, a diamond detector and thermoluminescence detectors TLD-600 and TLD-700. The yield of thermal neutrons was estimated for all radiation types while their complete spectrum was measured with bubble detectors during the irradiation with photons. The peripheral dose delivered by photons is significantly higher compared to both protons and carbon ions and exceeds the latter by up to two orders of magnitude at distances greater than 50 mm from the field. The comparison of passive and active delivery techniques for protons shows that, for the chosen rectangular target shape, the former has a sharper penumbra whereas the latter has a lower dose in the far-out-of-field region. When comparing scanning treatments, carbon ions present a sharper dose fall-off than protons close to the target but increasing peripheral dose with increasing incident energy. For photon irradiation, the contribution to the outof- field dose of photoneutrons appears to be of the same order of magnitude as the scattered primary beam. Charged particles show a clear supremacy over x-rays in achieving a higher dose conformality around the target and in sparing the healthy tissue from unnecessary radiation exposure. The out-of-field dose for x-rays increases with increasing beam energy because of the production of biologically harmful neutrons.

Dokumentart:Zeitschriftenbeitrag
Titel:Out-of-field dose measurements in a water phantom using different radiotherapy modalities
Autoren:
AutorenInstitution oder E-Mail-Adresse der Autoren
Kaderka, R. Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany
Schardt, D. Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany
Durante, M.Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany and Technische Universität Darmstadt, Darmstadt, Germany
Berger, T.German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany
Ramm, U. University Hospital, Johann Wolfgang Goethe Universität, Frankfurt/Main, Germany
Licher, J.University Hospital, Johann Wolfgang Goethe Universität, Frankfurt/Main, Germany
La Tessa, C.Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany
Datum:2012
Erschienen in:Phys. Med. Biol.
Referierte Publikation:Ja
In Open Access:Ja
In ISI Web of Science:Ja
Band:57
DOI :10.1088/0031-9155/57/16/5059
Seitenbereich:Seiten 5059-5074
Verlag:IOP PUBLISHING
Status:veröffentlicht
Stichwörter:Out-of-field dose measurements, water phantom, TLD, radiotherapy
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr, Verkehr und Weltraum (alt)
HGF - Programm:Raumfahrt, Weltraum (alt)
HGF - Programmthema:Forschung unter Weltraumbedingungen, W FR - Forschung unter Weltraumbedingungen (alt)
DLR - Schwerpunkt:Raumfahrt, Weltraum
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen, W FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Vorhaben Strahlenbiologie, W - Vorhaben Strahlenbiologie (alt)
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Strahlenbiologie
Hinterlegt von: Kerstin Kopp
Hinterlegt am:17 Aug 2012 11:21
Letzte Änderung:17 Aug 2012 11:21

Nur für Mitarbeiter des Archivs: Kontrollseite des Eintrags

Blättern
Suchen
Hilfe & Kontakt
Informationen
electronic library verwendet EPrints 3.3.12
Copyright © 2008-2013 Deutsches Zentrum für Luft- und Raumfahrt (DLR). Alle Rechte vorbehalten.