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Noninvasive Estimation of Myosin Heavy Chain Composition in Human Skeletal Muscle

Simunic, Bostjan und Degens, Hans und Rittweger, Jörn und Narici, Marco und Mekjavic, Igor und Pisot, Rado (2011) Noninvasive Estimation of Myosin Heavy Chain Composition in Human Skeletal Muscle. Medicine and Science in Sports and Exercise, 43 (9), Seiten 1619-1625. ISSN 0025-7990.

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Kurzfassung

Purpose: Information on muscle fiber type composition is of great importance in muscle physiology and athletic performance. Because there are only a few techniques available that noninvasively and accurately provide an estimate of muscle fiber type composition, the development of additional and alternative approaches is required. Methods: Twenty-seven participants (21 men, 6 women) with an average age of 43 T 18 yr, height of 175 T 7 cm, and mass of 74 T 12 kg participated in the study. Delay, contraction, and half relaxation times were calculated from tensiomyographic radial twitch responses of the vastus lateralis muscle. Univariate and multiple linear regression analyses were used to correlate the proportion of myosin heavy chain I (%MHC-I) in a biopsy obtained from the same muscle with a single and all three radial twitch parameters. Results: Delay, contraction, and half relaxation times all correlated with %MHC-I (r = 0.612, 0.878, and 0.669, respectively, at P e 0.001). When all three parameters were included in a multiple linear regression, the correlation with the %MHC-I was even better (R = 0.933, P G 0.001). Conclusions: These data suggest that time parameters of the skeletal muscle mechanical radial twitch response, measured with a contact linear displacement sensor, can be used as an accurate noninvasive predictor of the %MHC-I in a muscle.

Dokumentart:Zeitschriftenbeitrag
Titel:Noninvasive Estimation of Myosin Heavy Chain Composition in Human Skeletal Muscle
Autoren:
AutorenInstitution oder E-Mail-Adresse der Autoren
Simunic, BostjanUniversity of Primorska
Degens, HansManchester Metropolitan University
Rittweger, Jörnjoern.rittweger@dlr.de
Narici, MarcoManchester Metropolitan University, U.K.
Mekjavic, IgorJozef Stefan Institute
Pisot, RadoUniversity of Primorska
Datum:2011
Erschienen in:Medicine and Science in Sports and Exercise
Referierte Publikation:Ja
In SCOPUS:Ja
In ISI Web of Science:Nein
Band:43
Seitenbereich:Seiten 1619-1625
ISSN:0025-7990
Status:veröffentlicht
Stichwörter:TENSIOMYOGRAPHY, FIBER TYPE, MYOSIN HEAVY CHAIN, MECHANOMYOGRAPHY
HGF - Forschungsbereich:Luftfahrt, Raumfahrt und Verkehr
HGF - Programm:Raumfahrt
HGF - Programmthema:Forschung unter Weltraumbedingungen
DLR - Schwerpunkt:Raumfahrt
DLR - Forschungsgebiet:R FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):R - Vorhaben Integrative Studien
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Weltraumphysiologie
Hinterlegt von: Jörn Rittweger
Hinterlegt am:06 Dez 2011 12:21
Letzte Änderung:07 Feb 2013 19:44

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