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Variation in the determinants of power of chemically skinned type I rat soleus muscle fibres

Gilliver, Sally F und Jones, David A und Rittweger, Jörn und Degens, Hans (2011) Variation in the determinants of power of chemically skinned type I rat soleus muscle fibres. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 197, Seiten 311-319. ISSN 0340-7594.

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Kurzfassung

We explored to which extent maximal velocity of shortening (Vmax), force per cross-sectional area (specific tension, Po) and curvature of the force–velocity relationship (a/Po in the Hill equation) contribute to differences in peak power of single, chemically skinned rat type I fibres. Force–velocity relationships were determined from isotonic contractions of 94 maximally activated fibres. Peak power (±SD) was 3.50 ± 1.64 W L-1. There was a tenfold range of peak power and five-, six- and fourfold ranges for Po, Vmax and a/Po, respectively. None of the differences between fibres was explicable by differences in myosin heavy or light chain composition. The inverse relationship between a/Po and Vmax suggests a similar underlying cause. Fitting the data to the Huxley (Progr Biophys Biophys Chem 7:255–318, 1957) crossbridge model showed that the rate constant g2 and the sum of the rate constants (f ? g1) co-varied, both being low in the slowest fibres. Approximately 16% of the variation in Po could be explained by variation in the proportion of attached cycling cross-bridges (f/(f ? g1)), but the origin of most of the variance in Po remains unknown.

Dokumentart:Zeitschriftenbeitrag
Titel:Variation in the determinants of power of chemically skinned type I rat soleus muscle fibres
Autoren:
AutorenInstitution oder E-Mail-Adresse der Autoren
Gilliver, Sally FManchester Metropolitan University
Jones, David AManchester Metropolitan University
Rittweger, Jörnjoern.rittweger@dlr.de
Degens, HansManchester Metropolitan University
Datum:2011
Erschienen in:Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology
Referierte Publikation:Ja
In SCOPUS:Ja
In ISI Web of Science:Ja
Band:197
Seitenbereich:Seiten 311-319
ISSN:0340-7594
Status:veröffentlicht
Stichwörter:Skeletal muscle � Skinned fibres � Power � Force–velocity relationship
HGF - Forschungsbereich:Verkehr und Weltraum (alt)
HGF - Programm:Weltraum (alt)
HGF - Programmthema:W FR - Forschung unter Weltraumbedingungen (alt)
DLR - Schwerpunkt:Weltraum
DLR - Forschungsgebiet:W FR - Forschung unter Weltraumbedingungen
DLR - Teilgebiet (Projekt, Vorhaben):W - Vorhaben Integrative Studien (alt)
Standort: Köln-Porz
Institute & Einrichtungen:Institut für Luft- und Raumfahrtmedizin > Weltraumphysiologie
Hinterlegt von: Jörn Rittweger
Hinterlegt am:16 Jun 2011 12:37
Letzte Änderung:12 Dez 2013 21:16

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